摘要
目的探讨不同年龄人群双气囊小肠镜（DBE）检查对不明原因消化道出血（OGIB）的诊断价值。方法回顾性分析2007年1月至2012年1月间武汉大学人民医院消化内科和胃肠外科因OGIB行DBE检查的216例患者的临床资料。按年龄分为青年组（小于或等于40岁）86例，中年组（41～59岁）81例，老年组（大于或等于60岁）49例，比较不同年龄组患者DBE的病变检出情况。结果青年组憩室．小肠重复畸形和克罗恩病的检出率分别为37．2％（32／86）和15．1％（13／86），明显高于中年组[16．0％（13／81）和9．9％（8／81），均P〈0．01]和老年组[10．2％（5／49）和0／49，均P〈0．01]；但其肿瘤检出率（12．8％，11／86）则明显低于中年组（30．9％，25／81）和老年组（22．4％，11／49）（均P〈0．01）。3组患者DBE检查的诊断率分别为83．7％（72／86）、87．7％（71／81）和81．6％（40／49），差异无统计学意义（P〉0．05）；并发症发生率分别为1．2％（1／86）、2．5％（2／81）和2．0％（1／49），差异无统计学意义（P〉0．05）。结论DBE是一种安全、有效的诊断OGIB的检查方法，适用于各年龄人群。不同年龄人群OGIB病因具有各自特点，应根据这些特点制订有效的诊治策略。
Objective To investigate the diagnostic value of double balloon enteroscope （DBE） on obscure gastrointestinal bleeding （OGIB） and to analyze etiological characteristics among different age groups. Methods The clinical data of patients undergoing DBE due to OGIB in the Department of Gastroenterology in Renmin Hospital of Wuhan University from January 2007 to January 2012 were retrospectively analyzed and compared among different age groups. Patients were divided into the young group（age〈~40, n=86）, the middle age group（aged 41-59, n=81）, and the elderly group （age ~〉60, n=49）. The detection of bleeding origin by DBE was compared between different age groups. Results Diagnosis rates in young, middle age, elderly group were 83.7%（72/86）, 87.7%（71/81）, 81.6% （40/49） without statistical differences （P〉0.05）. Complication rates in the young, middle age, and elderly group were 1.2% （1/86）, 2.5% （2/81 ）, 2.0% （1/49） without statistic difference （P〉0.05）. The most common cause in young group was diverticulum/replica malformation while the most common location was ileum. The most common cause in both middle age and elderly group was tumor. Conclusions DBE is an effective and safe method for diagnosis of OGIB among different age groups. Each age group has its etiological characteristics. Diagnosis and therapeutic strategy based on age related characteristics is worthy of further investigation.
出处
《中华胃肠外科杂志》
CAS
CSCD
2013年第5期434-438,共5页
Chinese Journal of Gastrointestinal Surgery
关键词
双气囊小肠镜
不明原因消化道出血
年龄
病因诊断
Double balloon enteroscope
Obscure gastrointestinal bleeding
Age
Etiologicaldiagnosis
