摘要
目的系统评价CT灌注成像对孤立性肺结节的定性诊断价值。方法通过检索中国知网(CNKI)、Pubmed和万方数据库,收集以CT灌注成像对孤立性肺结节进行诊断的相关文献。比较良恶性孤立性肺结节灌注参数的血流量、血容量、平均通过时间和表面通透性。结果 10篇文献纳入本次研究,Meta分析显示:良性结节组血流量数值、血容量和表面通透性值比恶性结节组小,其加权均数差(WMD)及95%CI分别地为-60.98(-1.43,-0.60)、-5.71(-7.29,-4.13)和-15.18(-18.95,-11.41)。结论良恶性肺结节血流量、血容量和表面通透性数值具有差异性。
Objective Meta evaluation the value of the qualitative diagnostic of solitary puhnonary nodules by CT perfusion imaging. Methods Collect the literatures about the diagnosis of solitary puhnonary nodules in CT perfusion imaging by searching Pubmed, CNKI and Wanfang Database in order to cmnpare between the benign SPN and the malig- nant SPN by measuring the perfusion parameter include parameter of w~/ume of blood flow, volume of blood, mean transit time and permeability-surface area. Results The ten studies were included in this study. Meta-analysis shows that the parameter of volume of blood flowiCvolume of blood and permeability-surface for the benign was smaller than that of malignant in Solitary Pulmonary Nodule, the WMD（95%CI） was -60.98（-1.43,-0.60）, 5. 71 （-7.29,-4.13） and - 15.18（- 18.95,- 11.41 ）. Conclusion There was difference between the benign and malignant of Solitary Pulmonary Nodule in volume of blood flow, volume of blood and permeability-surface, which can used to diagnose the solitary pulmonary nodules.
出处
《中国CT和MRI杂志》
2013年第2期22-24,30,共4页
Chinese Journal of CT and MRI
