摘要
在模拟人体温度 37℃条件下 ,进行硅灰石纤维粉尘与氨基酸作用的实验研究 ,测定在 72h内溶解过程中pH值和电导率 (κ)的变化。结果表明 ,硅灰石纤维矿物在氨基酸中发生的溶解作用与酸的性质有关 ,酸性氨基酸对矿物的溶解能力最强 ,中性次之 ,碱性最弱。硅灰石在酸性和碱性氨基酸中 8h左右出现溶解饱和点 ,而在中性氨基酸中 72h内无溶解饱和点 ,溶解度具有随时间的增加而呈线性增长的趋势。硅灰石的这种溶解特征表明 ,硅灰石在近中性的体液中长期耐久性不高 ,金属离子能被氨基酸所活化和迁移 ,溶解过程中金属离子与氨基酸发生的有机配合反应对氨基酸结构产生一定的破坏 ,有可能是导致正常的蛋白质受破坏的原因之一。
The process of dissolution of fibrous wollastonite dust in amino acid aqueous solution at body's temperature 37℃ was studied and the variations of pH and conductivity in 72 hours in the dissolution process were measured. Results suggest that the dissolution of wollastonite fibers in amino acids is related to the nature of acid: the capacity of mineral's dissolution is strongest in acid amino acids, less strong in neutral amino acids and weak in alkali amino acids. The saturation point appears in about 8 hours when the mineral is in acid and alkali amino acids, while in neutral amino acids no saturation point appears within 72 hours. The solubility has a trend of increasing linearly with time. The dissolution characters of wollastonite show that wollastonite's resistibility is not strong in nearly neutral body liquid. Metal ions can be remobilized by amino acids, and in the process of dissolution the organic reaction between metal ions and amino acids may damage the structure of amino acids to some extent, which may be one of the causes for the damage of normal protein.
出处
《岩石矿物学杂志》
CAS
CSCD
北大核心
2000年第3期206-211,共6页
Acta Petrologica et Mineralogica
基金
国家自然科学基金项目!(编号 :4 950 2 0 2 5)的资助
