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二氢嘧啶脱氢酶在大肠癌的表达及其与5-氟尿嘧啶化疗敏感性的研究

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摘要 本研究通过免疫组织化学检测大肠癌中二氢嘧啶脱氢酶（DPD）的表达情况,结合体外药敏试验,探讨DPD表达水平与5-氟尿嘧啶（5-FU）化疗敏感性的相关性,从中分析药物代谢相关酶的表达情况,为临床开展耐药指标筛查,指导大肠癌个体化疗提供理论依据。
作者 司志英 王长征 靳英
机构地区 忻州职业技术学院医学系检验教研室 忻州市人民医院病理科
出处 《中国药物与临床》 CAS 2013年第5期587-589,共3页 Chinese Remedies & Clinics
关键词 二氢嘧啶脱氢酶 5-氟尿嘧啶 化疗敏感性 大肠癌 免疫组织化学检测 体外药敏试验 表达情况 药物代谢
分类号 R735.34 [医药卫生—肿瘤]
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中国药物与临床
2013年 第5期

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