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脂联素与血管内膜增生的研究进展 被引量：5

Adiponectin and intimal hyperplasia
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摘要 脂联素(Adiponectin,APN)是脂肪源性特异性蛋白,目前研究证实APN在心血管系统具有重要的保护作用,APN具有抑制内皮细胞炎症及黏附、巨噬细胞向泡沫细胞转变、平滑肌细胞增殖及改善糖脂代谢等功能,与血管内膜增生后血管狭窄有密切相关,是一种潜在的预防血管狭窄的重要生物分子靶点。文中就APN与血管内膜增生的潜在关系作一综述。 [ Abstract ]inhibiting endothelial cell inflammation and adhesion, macrophage transformation to foam cells, and vascular smooth muscle cell proliferation, as well as by improving glucolipid metabolism. Closely related to vascular stenosis from intimal hyperplasia, adiponectin is a potential bio- molecular target for the prevention of vascular stenosis. This review summarizes the potential relationship between adiponectin and vas- cular intimal hyperplasia.
作者 刘小龙 李徳闽
机构地区 南京大学医学院(南京军区南京总医院)心胸外科
出处 《医学研究生学报》 CAS 北大核心 2013年第4期407-410,共4页 Journal of Medical Postgraduates
基金 国家"863"项目(2006AAOA1397)
关键词 脂联素 内膜增生 血管狭窄 Adiponetin Intimal hyperplasia Vascular stenosis
分类号 R543 [医药卫生—心血管疾病]
  • 相关文献

参考文献28

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二级参考文献18

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共引文献5

同被引文献57

  • 1Rima Hage Hassan,Olivier Bourron,Eric Hajduch.Defect of insulin signal in peripheral tissues: important role of ceramide[J].World Journal of Diabetes,2014,5(3):244-257. 被引量：9
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引证文献5

二级引证文献17

医学研究生学报
2013年 第4期

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