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复发性病毒性脑炎的临床特点(附2例报告) 被引量:1

Clinical features of relapsing viral encephalitis(report of 2 cases)
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摘要 目的探讨复发性病毒性脑炎的临床特点。方法回顾性分析2例复发性病毒性脑炎患者的临床资料。结果 2例患者中1例男性(71岁),1例女性(35岁),临床表现为反复发作的癫痫伴智能或意识障碍、失语等;影像学检查示病灶多发于脑皮质,均伴颞叶受累;脑电图以广泛慢波为主。给予足量抗病毒药物及糖皮质激素治疗后,症状明显好转,随访2~4个月未见复发。结论复发性病毒性脑炎患者的临床表现以颞叶症状为主,其发病机制可能为病毒的再激活所致,早期足量抗病毒治疗效果较好。 Objective To investigate the clinical features of relapsing viral encephalitis. Methods The clinical data of 2 patients with relapsing viral encephalitis -kas analyzed retrospectively. Results Two cases were one male (71 years old) and one female (35 yeal"s old). The clinical manifestation of the 2 patients were epilepsy with repeatedly seizure, disturbance of intelligence or consciousness and aphasia, etc. Imaging detection showed that lesions mostly suffered in cortex, especially in the temporal lobe. EEG revealed wide range of slow-wave-based. After treating with sufficient antiviral medicine and glucocorticoid their symptoms markedly improved, and they were follow- up for 2 - 4 months without recurrence. Conclusions The clinical manifestation of relapsing viral encephalitis is mainly as temporal lobe symptoms. The mechanism is possibly owing to reactivation of the virus. The efficacy of sufficient and early antiviral treatment is good.
出处 《临床神经病学杂志》 CAS 北大核心 2013年第2期147-149,共3页 Journal of Clinical Neurology
关键词 复发性病毒性脑炎 临床 特点 relapsing viral encephalitis clinical features
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参考文献7

  • 1Kennedy PG. Viral encephalitis[J]. J Neurol, 2005, 252: 268.
  • 2黄颜,刘秀琴,杨荫昌,高晶.复发性病毒性脑炎的临床特点和发病机制探讨[J].中华医学杂志,2008,88(31):2183-2186. 被引量:6
  • 3Spiegel R, Miron D, Yodko H, et al. Late relapse of herpes sim- plex virus encephalitis in a child due to reactivation of latent virus: clinicopathological report and review [ J ]. J Child Neurol, 2008, 344 : 348.
  • 4D Ku B, Sang Yoon S. Relapsing herpes simplex encephalitis resul- ting in Kluver-Bucy syndrome [ J ]. Intern Med, 2011, 50 : 763.
  • 5Rathi N, Rathi A. Relapse of herpes simplex encephalitis presenting as choreoathetosis[J]. Indian J Pediatr, 2010, 901 : 902.
  • 6Yamada S, Kameyama T, Nagaya S, et al. Relapsing herpes sim- plex encephalitis: pathological confirmation of viral reactivation[ J]. J Neurol Neurosurg Psychiatry, 2003, 262 : 264.
  • 7Chang T, Riffsy MT, Gunaratne PS. Hashimoto eneephalopathy: clinical and MRI improvement following high-dose eorticosteroid therapy[J]. Neurologist, 2010, 394: 396.

二级参考文献8

  • 1Najioullah F, Bosshard S, Thouvenot D, et al. Dignosis and surveillance of herpes simplex virus infection of the central nervous system. J Med Virol, 2000, 61: 468-473.
  • 2Jackson AC, Melanson M, Rossiter JP. Familial herpes simplex encephalitis. Ann Neurol, 2002, 51:406-407.
  • 3Gutienrez. KM, Prober CG. Encephalitis. Identifying the specific cause is key to effective management. Postgrad Med, 1998,103: 123-125, 129-130,140-143.
  • 4Ito Y, Kimura H, Yabuta Y, et al. Exacerbation of herpes simplex encephalitis after successful treatment with acyclovir. Clin Infect Dis, 2000, 30:185-187.
  • 5Tiege XD, Rozenberg F, Portes VD, et al. Herpes simplex encephalitis relapses in children. Neuorology, 2003,61:241-243.
  • 6Yamada S, Kameyama T, Nagaya S, et al. Relapsing herpes simplex encephalitis: pathological confirmation of viral reactivation. J Neurol Neurosurg Psychiatry, 2003, 74: 262-264.
  • 7Joos AAB, Ziyeh S, Rauer S, et al. Postinfectious autoimmunemediated encephalitis eight months after herpes simplex encephalitis. Eur Neurol, 2003, 50:54-56.
  • 8Lellouch-Tubiana A, Fohlen M, Robin O, et al. Immunocytochemical characterization of long-term persistent immune activation in human brain after herpes simplex encephalitis. Neuropathol Appl Neurobiol, 2000, 26 : 285-294.

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