期刊文献+

亚低温技术在心脏骤停后综合征脑保护治疗中的应用 被引量:9

Application of mild hypothermia in post-cardiac arrest syndrome brain protection
暂未订购
导出
摘要 心脏骤停患者自主循环恢复后易产生广泛的组织器官损伤,亚低温(32~34℃)治疗能改善预后和使患者获益。临床上可以选用降温毯、冷液体快速静脉输注、自粘型水凝胶包被、血管内冷却降温、冰敷冰帽等多种措施使体温降低。一般认为在心肺复苏后0.5~0.6h内开始降温是一个合适的"亚低温治疗时间窗",低温时间l2~24h,然后缓慢(0.25~0.5℃/h)复温到36.5℃。寒战、肺部感染、低血压、心律失常、血小板减少是低温治疗过程中常见的不良反应。 The cardiac arrest patients after the return of spontaneous circulation caused organ damage extensive, mild hypothermia (32 -34 ℃ ) treatment could improve the prognosis and bring many benefit to the patients. Cooling blankets, cold liquid rapid intravenous infusion, self-adhesive hydrogel coated intravascular cool-down, ice cap and other measures are used to lower the body temperature. It was generally considered that starting to lower the temperature of the patients within 0.5-0.6 h after cardiopulmonary resuscitation was a suitable "mild hypothermia therapy time window", maintaining the low temperature 12 to 24 hours, and then rewarming slowly (0.25-0.5 ℃/h) to the temperature of 36.5 ℃ . Chills, lung infection, hypotension, arrhythmias, thrombocytopenia were the common adverse reactions during the process of mild therapeutic hypothermia.
出处 《中国医药科学》 2013年第8期52-54,共3页 China Medicine And Pharmacy
关键词 心脏骤停后综合征 亚低温技术 应用 不良反应 Post-cardiac arrest syndrome Mild hypothermia Application Adverse reactions
  • 相关文献

参考文献24

  • 1Negovsky VA, Gurvitch AM.Post-resuscitation disease a new nosological entity.Its reality and signifieance[J].Resuscitation, 1995,30 ( 1 ) : 23-27.
  • 2Nolan JP, Neumar RW, Adrie C, et al.Post-cardiac arrest, syndrome: epidemiology, pathnphysiology, treatment, and prognostication. A scientific statement from the international liaison committee on resuscitation;the american heart association emergency cardiovascular care committee;the council on cardiovascular surgery and anesthesia; the council on cardiopulmonary,perioperative, and critical care, the council on clinical cardiology; the council on stroke[J].Resuscitation, 2008,79 ( 3 ) : 350-379.
  • 3Soar J, Nolan JP. Mild hypothermia for post cardiac arrest syndrome[J]. BMJ,2007,335 ( 7618 ): 459-460.
  • 4李道海,林锦潮,梁子敬,李平,曾量波.亚低温治疗对院内心脏停搏患者神经功能和预后的影响[J].中国医药指南,2012,10(1):5-7. 被引量:6
  • 5王慧贤,余厚友,尹文.亚低温对急性脊髓损伤后肿瘤坏死因子-α表达及运动功能恢复的影响[J].中国急救医学,2012,32(3):223-226. 被引量:6
  • 6李娜,李世英,夏静.亚低温对局灶性脑缺血再灌注大鼠脑皮质神经元凋亡及存活素、脑源性神经营养因子表达的影响[J].中风与神经疾病杂志,2012,29(3):239-242. 被引量:11
  • 72010 American heart association guideline for CPR and ECC.Part 12 postresuseitation support[J]. Circulation,2010,122: s640-656.
  • 8American association of neurological surgeons. Congress of neurological surgeons, guidelines for the management of severe traumatic brain injury[J]. J Neurotrauma,2007,24 ( Suppl 1 ): S1-106.
  • 9张新超.心脏骤停后综合征[J].中国心血管杂志,2010,15(5):340-342. 被引量:10
  • 10Jammn H, Knutsson L, Rundgren M, et al. Difusion and perfusion MRI of the brain in cxmatose patients treated with mild hypothermia after cardiac arrest: a prospective observational study[J].Resuscitation,2009,80 ( 4 ) : 425-430.

二级参考文献65

  • 1孙志扬,李光,孙庆文,黄兴华,刘娜.亚低温对心肺复苏大鼠大脑额叶皮层NMDAR1表达的影响[J].中华急诊医学杂志,2006,15(1):27-30. 被引量:13
  • 2张广军.亚低温疗法的临床应用[J].医学理论与实践,2006,19(2):154-155. 被引量:11
  • 3Holzer M,Bernard SA, Hachimi Idrissi S, et al.Hypothermia for neuroprotection after cardiac arrest: Systemic review and individual patient data meta-analysis[J].Crit Care Med,2005,33(2):414-418.
  • 4American Heart Association.Heart disease and stroke statistics:2002 update[S].Dallas,TX:American Heart Association,2001.
  • 5Felberg RA,Krieger DW,Chuang R,et al.Hypothermia after cardiac arrest:feasibility and safety of an external cooling protocol[J].Circulation,2001,104(15):1799-1804.
  • 6Al-senani FM,Graffagnino C,Grotta JC,et al.A prospective,multicenter pilot study to evaluate the feasibility and safety of using the CoolGard System and Icy catheter following cardiac arrest[J].Resuscitation,2004,62(2):143-150.
  • 7Introduction to the international guidelines 2000 for CPR and ECC.A consensus on science.European Resuscitation Council[J].Resuscitation,2000,46(1-3):3-15.
  • 8Michael H,Wilhelm B.Therapeutic hypothermia after cardiac arrest[J].Curr Opin Anaesthesiol,2005,18(2):163-168.
  • 9Polderman KH.Application of therapeutic hypothermia in the ICU:opportunities and pitfalls of a promising treatment modality.Part 1:Indications and evidence[J].Intensive Care Med,2004,30(4):556-575.
  • 10Xu L,Yenari MA,Steinberg GK,et al.Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade[J].J Cereb Blood Flow Metab,2002,22(1):21-28.

共引文献66

同被引文献86

引证文献9

二级引证文献103

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部