摘要
研究活动期溃疡性结肠炎 (UC)的内镜特点 ,以及与主要临床表现的关系。方法 :采用改进的Baron关于UC内镜下活动分级标准对 70例UC患者进行分析 ,并采用Spearman等级相关分析其与主要临床表现的关系。结果 :本组病例中 ,活动度为Ⅰ级占 15 .7% ,Ⅱ级占 2 4.3% ,Ⅲ级占 12 .9% ,Ⅳ级占 47.1%。病变范围 :直肠占 12 .9% ,直肠乙状结肠占 34.3 % ,左半结肠占 2 2 .9% ,右半结肠占 2 .8% ,区域型占 2 .8% ,全结肠占 2 4.3 % ,发生左侧远端结肠者占 70 %。合并息肉为 2 2 .9% ,不典型增生为 7.1% ,直肠上段缩窄为 1.3% ,淋巴瘤为 1.3 %。结肠镜下活动度分级与临床活动指数AI(r=0 .37,P <0 .0 1) ,ESR(r=0 .2 7,P <0 .0 5 ) ,粘液血便的程度 (r=0 .32 ,P <0 .0 1)及次数 (r =0 .2 5 ,P <0 .0 5 )有一定的关联 ,与血红蛋白 (r =- 0 .2 1,P >0 .0 5 ) ,血浆白蛋白 (r =- 0 .2 3 ,P >0 .0 5 )无显著关系。结论 :活动期UC的内镜特点 :活动度以Ⅳ级和Ⅱ级为主 ,病变范围以左侧远端结肠直肠为主 ,息肉发生率为 2 2 .9% ,不典型增生为 7.1% ,内镜下UC的活动度与AI、ESR、粘液血便的程度及次数有一定的关联。
Objective: The study investigated endoscopic features and it correlative with clinical expression in the patients with active period of ulcerative colitis (UC). Methods: We make restrospective analysis according to improve Baron's active classification in 70 patients with UC. Results: The endoscopic activity according to Baron's classification: There are 12.9 percent Grad I, and 24.3 percent Grad II, and 12.9 percent Grad III, and up to 47.1 percent Grad IV. Extent of disease: proctitis is12.9 percent, and proctosigmoiditis is 34.3 percent, and left-sided colitis is 22.9 percent, and right-sided colitis is 2.8 percent, and total colitis is 24.3 percent, and regional colitis is 2.8 percent, but also under-left-sided colitis are up to 70 percent. Complications: The incidence rate of polyp is 22.9 percent, and atypical proliferation is 7.1 percent, and contract up-retumed is 1.3 percent, and lymphosarcoma is 1.3 percent. The significant positive correlative with independent variables: AI r=0.37, P <0.005, ESR r=0.27, P <0.05, Bloody stool r=0.32, P <0.01, Bowel movements r=0.25, P <0.05; No markable correlation with Hemoglobin and Albumin. Conclusions: The endoscopic features of active UC are mainly Grad II and Grad IV. Extent of UC is mainly under left-sided colitis. The incidence rate of polyp is 22.9 percent, and atypical proliferation is 7.1 percent. There is a significant positive correlation between endoscopic activity and AI or ESR or bloody stool or bowel movements.
出处
《中国内镜杂志》
CSCD
2000年第4期7-8,共2页
China Journal of Endoscopy
