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杭州市男男性行为人群HIV和梅毒螺旋体血清抗体阳转情况队列研究 被引量:4

A prospective cohort study on positive seroconversion of HIV and Treponema pallidum antibodies among men who have sex with men in Hangzhou
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摘要 目的了解杭州市男男性行为人群(MSM)的艾滋病病毒(HIV)和梅毒螺旋体血清抗体阳转情况。方法于2011年6月在杭州市上城区、下城区、江干区、拱墅区和西湖区5个主要城区的自愿咨询检测门诊招募80名MSM组建队列。在基线、3个月和6个月调查其高危行为情况,并采集血样检测HIV和梅毒螺旋体血清抗体。结果基线调查纳入80名HIV抗体阴性的调查对象,梅毒螺旋体阳性率为3.75%(3/80)。队列随访6个月,MSM队列保持率为92.5%(74/80),HIV血清抗体阳转率为10.7/100人年,梅毒阳转率为13.9/100人年。结论杭州市MSM人群HIV和梅毒血清阳转情况十分严重。应加大该人群的艾滋病宣传干预力度,探索开展更为有效的干预措施。 Objective To understand the positive seroconversion of human immunodeficiency virus (HIV) and Treponema pallidum antibodies among men who have sex with men (MSM) in Hangzhou. Methods MSM were recruited from HIV voluntary counsel and test (VCT) clinics in 5 districts in Hangzhou, and follow up for 3 and 6 months was made among them to learn about their high risk behaviors. Blood samples were taken from them to detect the antibodies to HIV and Treponema pallidum. Results Among 80 HIV negative MSM recruited, 3.75% (3/80) were Treponema pallidum positive, 92. 5 % (74/80) completed the 6 month follow up. The positive seroconversion rates of HIV and Treponema pallidum antibodies were 10. 7/100 person-years and 13.9/100 person-years respectively. Conclusion The positive seroconversion of HIV and Treponema paUidum in this MSM cohort was very serious. More effective measures should be taken to reduce the prevalence of HIV infection and syphilis in MSM in Hangzhou.
出处 《疾病监测》 CAS 2013年第4期280-283,共4页 Disease Surveillance
关键词 同性恋 男性 艾滋病病毒 梅毒 抗体 men who have sex with men human immunodeficiency virus syphilis antibody
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