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局部进展期结肠癌扩大切除术疗效分析

Observation of clinical effect of extended resection forlocally advanced carcinoma of colon
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摘要 目的探讨局部进展期结肠癌扩大根治术并发症防治并评价其疗效。方法对48例行扩大根治术的结肠癌病例临床资料进行分析。结果手术并发症发生率为6 3%(3/45) ,死亡率2 1 %(1/48) ,术后5年生存率52 1 %(25/48) ,与本院同期行结肠癌根治术病例相近 ,其中恶性程度较高的粘液腺癌和未分化癌5年生存率低于其它类型肿瘤。N3 淋巴结转移者疗效显著下降。结论扩大根治术防止并发症的关键是围手术期处理和切除范围的选择 ,提高生存率应从确保局部无肿瘤残留和足够的淋巴结清扫方面努力。 Objective: To expolre the prevention and cure of the reducible extended surgical complication in the patients with locally advanced carcinona of colon and to estimate the effects of extended resection.Methods:The clinical data of 48 patients who received extended resection were retrospectively analyzed Results The incident morbidity was 6.3%(3/48).The mortality rate was 2.1%(1/48) The 5 years survival rate was 52.1(25/48). In the patients with mucinous carcinoma and nondifferentiated carcinoma,the 5 years survival rate was significantly lower than that in those with other subtypes.when the lymph nodal stage was N3,the curative effect of the operation was significantly decreased.Conclusion:In extended resection for those patients,apporiate perioperative management and excisional range selection are most important to prevent complication.To improve the survival rate great effort should be made to ensure non residual tumor and adequte lymphic node dissection.[
出处 《井冈山医专学报》 2000年第3期10-11,共2页 Journal of Jinggangshan Medical College
关键词 结肠癌 扩大 存活率 外科手术 切除术 intestinal neoplasm colon carcinoma surgery operation survival rate
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参考文献2

  • 1Lopez MJ,Monafo WW. Role of extended resection the initial treatment of locally advanced Colorectal carcinoma[J].Surgery,1993,113(4):365 372.
  • 2Dudoey H,etal.Imtraopreativc of the Colon to premit primary annstomosis[J] Br J Surg.1980,67:80.

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