摘要
目的探讨利巴韦林滴鼻对小儿急性上呼吸道感染的疗效。方法将132例急性上呼吸道感染的患儿随机分为治疗组和对照组。对照组给予常规抗病毒、对症支持等治疗,治疗组在对照组基础上给予利巴韦林滴鼻,用法:将利巴韦林针0.1g加入0.9%氯化钠针10mL配成滴鼻液,3～6个月,1滴;6个月～1岁,2滴;1.1～3.0岁,3滴;3.1～6.0岁,3～4滴,均滴双侧鼻孔。第1个1小时每15分钟滴1次,以后每2小时滴1次,3d为1个疗程,连用1～2个疗程。结果治疗组总有效率为91.7%,对照组总有效率为78.3%,两组比较差异有统计学意义(P<0.05)。治疗组的症状改善时间优于对照组(P<0.01)。结论利巴韦林滴鼻治疗小儿急性上呼吸道感染能够缩短病程,起效快,临床疗效好,方法简便,值得临床推广。
Objective To study clinical efficacy of Ribavirin Nasal Dropping on treatment of infantile acute upper res- piratory tract infection. Methods One hundred and thirty-two infants with acute upper respiratory tract infection were randomly divided into trial group and control group. The control group was given conventional treatment. The trial group was given treatment of Ribavirin Nasal Dropping on the basis of conventional treatment. was made of 0.1 g Ribavirin injection combined with 10 mL 0.9% sodium chloride injection. 3 months to 6 months old infants were given one drops. And the 6-month-olds to 12-month-olds were given 2 drops. The 1.1-3.0-year-olds were given 3 drops. And the 3.1-6.0-year-olds were given 3 to 4 drops. Both nostrils were given drops. 3 days was a treatment and the infants were given one to two courses. Results The total effective rate of the trial group and the con- trol group was 91.7% and 78.3% respectively. There was a significant difference between two groups （P 〈 0.05）. The symptom improvement time of the trial group was less the length of the disease and has a good clinical effect （P 〈 0.01）. Conclusion Ribavirin nasal dropping can shorten
出处
《中国当代医药》
2013年第11期36-37,共2页
China Modern Medicine
关键词
利巴韦林
滴鼻
上呼吸道感染
疗效
Ribavirin nasal
Dropping
Upper respiratory tract infection
Efficacy
