摘要
目的观察高渗盐水雾化吸入联合红霉素口服辅治婴儿毛细支气管炎的临床疗效。方法将67例毛细支气管炎患儿随机分为观察组29例和对照组38例。2组均予常规对症支持治疗,在此基础上,对照组予生理盐水雾化吸入治疗;观察组予3%高渗盐水雾化吸入联合红霉素口服治疗。观察2组喘息缓解时间、咳嗽缓解时间、住院时间、呕吐次数及不良反应。结果观察组喘息缓解时间、咳嗽缓解时间及住院时间均短于对照组,呕吐次数少于对照组,差异均有统计学意义(P<0.05或P<0.01)。2组均未见特殊不良反应发生。结论高渗盐水雾化吸入联合红霉素口服辅治婴儿毛细支气管炎临床疗效显著,无特殊不良反应,值得临床推广应用。
Objective To observe the effect of hypertonic saline atomization inhalation combined with erythromycin o- ral in the treatment of infants bronchiolitis. Methods 67 cases children with infant bronchiolitis were randomly divided into observation group（29 eases）and control group （38 cases）. Both of 2 groups were given symptomatic and supportive treatment, on basis of that, control group were treated with normal saline atomization inhalation, and observation group were treated with 3% hypertonic saline atomization inhalation combined with oral erythromycin. The gasp relief time, cough relief time, hospital stay time, vomiting frequency and adverse reactions of two groups were observed. Results The gasp relief time, cough relief time, hospital stay time of observation group were shorter than that of control group, vomiting frequency of observation group was less than that of control group, the difference was statistically significant （P 〈 0.05 or P 〈 0.01 ）. There was no special adverse reactions in 2 groups. Conclusion The treatment of hypertonic saline atomization inhalation combined with erythromycin oral has better curative effect, and no adverse reaction, worth of clinical application.
出处
《临床合理用药杂志》
2013年第10期43-44,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
毛细支气管炎
婴儿
高渗盐水
红霉素
Bronchiolitis
Infants
Hypertonic saline
Erythromycin
