摘要
目的探讨热毒宁注射液引起过敏性休克的临床表现及诊治经验,以提高认识,减少或避免热毒宁注射液所引起的不良反应。方法报道热毒宁注射液致过敏性休克患儿1例,并结合国内近10年来己报道的热毒宁不良反应,特别是过敏性休克进行文献复习。结果热毒宁注射液的不良反应以皮肤症状为最常见,比例为62.37%;其次到消化系统,比例为7.92%,最少见的为血尿与神经系统症状,仅占0.99%;发生过敏性休克的以男性3～4岁的患儿较多见,且发生休克的时间大多在输液开始30min内。结论热毒宁注射液的不良反应大多轻微,严重不良反应较少;对于3～4岁的男性患儿使用热毒宁注射液治疗时,要严格按使用说明书进行输液,在30min内要特别观察,以避免过敏性休克的发生。
Objective To investigate clinical manifestations and diagnosis and treatment experience of Reduning injec- tion caused anaphylactie shock, in order to improve the understanding, reduce or avoid Reduning injection caused by the adverse reaction. Methods Reported one ease of Reduning injection to anaphylactic shock, and review the literature of Reduning injec- tion adverse reaction, especially anaphylactie shock with the nearly ten years has reported. Results Reduning injection adverse reactions to the skin was the most common symptoms, the proportion is 62. 37%, and the digestive system, the proportion is 7. 92% , the most rare for hematuria and nervous system symptoms, only 0. 99% ; Anaphylactic shock often occurred in male 3 ~ 4 years old of children, and the time of shock mostly began in 30 minutes. Conclusion Reduning injection adverse reactions are mild, serious adverse reaction less; For 3 -4 years old children of men use Reduning injection treatment, must strictly ac- cording to the instruction for use for infusion, observe specially in 30 minutes, in order to avoid the occurrence of anaphylactic shock.
出处
《临床合理用药杂志》
2013年第12期147-148,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
热毒宁
过敏性休克
不良反应
Reduning
Anaphylactic shock
Adverse reaction
