摘要
体外转化在四环三萜皂苷类活性成分方面的应用,可提高其的生物利用度、节省药材、提高苷类制剂的普适性,同时可为发掘四环三萜皂苷起效的物质基础提供依据。文章对四环三萜皂苷类活性成分生物利用度、肠道吸收及体外转化应用等方面进行了综述。
The application of transformation in tetracyclic triterpenoid saponins of active ingredients in vitro can improve the drug bioavailability, save medicinal materials and improve the universality of the preparation, and provide the basis of discovering the real tetracyclie triterpenoid saponins material basis of effect. In this paper, tetracyclic triterpenoid saponins of active ingredient laioavailability, intestinal absorption and application in vitro transformation and so on were reviewed.
出处
《辽宁中医药大学学报》
CAS
2013年第5期102-105,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
山东省自然科学基金资助项目(ZR2011HL043)
关键词
四环三萜皂苷
肠道吸收
体外转化
tetracyelie triterpenoid saponins
intestinal absorption
transformation in vitro
