摘要
目的探讨动脉血管内灌注维拉帕米治疗神经介入手术中脑血管痉挛的有效性及安全性。方法脑动脉瘤介入术中出现的影像学脑血管痉挛15例,均经导管向动脉血管内灌注维拉帕米治疗。比较灌注前、后脑血管直径的变化,并记录灌注治疗过程中患者的心率和平均动脉压。结果本组15例共实施了15根脑动脉血管内的灌注治疗,11例痉挛血管获得影像学改善。灌注前、后心率和平均动脉压均无明显改变[(78±11)次/分vs.(79±12)次/分和(108±13)mm Hg vs.(110±14)mm Hg](P>0.05)。结论动脉血管内灌注维拉帕米治疗脑动脉瘤介入术中的脑血管痉挛安全、有效。
Objective To investigate the efficacy and safety of verapamil used intra-arterial infusion for treating cerebral vasospasm during intervention therapy of cerebral aneurysrm Methods Verapamil 5 mg in normal saline 10 ml was infused in 1 min via intra-arterial catheter（repeated not more than 3 times） for treating cerebral vasopasm happened angiographically in 15 cases. The diameter of blood vessels, mean artery pressure（MAP） and heart rate（HR） were compared before and after treatment. Results Of 15 patients, vasospasm on digital subtraction angiography（DSA） was improved in 11 cases. HR and MAP were not significantly changed before and after treatment[（78 ± 11） beats/min vs. （79± 12） beats/min and （108 ±13） mm Hg vs. （110 ± 14） mmHg] （P〉0. 05）. Conclusion It is effective and safe to treat vasospasm with verapamil via intra-arterial catheter during intervention therapy of cerebral aneurysm.
出处
《江苏医药》
北大核心
2013年第8期938-940,共3页
Jiangsu Medical Journal
基金
江苏省江阴市科技局项目[澄政科(2011)85号]
关键词
维拉帕米
脑血管痉挛
脑动脉瘤
Verapamil
Cerebral vasopasm
Cerebral aneurysm
