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婴幼儿肺炎支原体126例临床分析 被引量:1

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摘要 目的探讨婴幼儿肺炎支原体肺炎(MPP)的临床特点。方法对126例婴幼儿MPP的临床资料进行回顾性分析。结果婴幼儿MPP患儿(126例)占同期所有MPP患儿(281例)的44.8%。临床表现以咳嗽、发热为主,72%伴有喘息,84%可闻及肺部湿啰音和(或)喘鸣音。32.6%出现肺外表现,以心肌酶升高最为常见。胸部影像学检查双肺均可累及,以右、双下肺受累最常见,多为斑片状、大片状阴影。病程10 d之后检测血清MP-IgM 100%阳性。多数血白细胞计数在正常范围,C-反应蛋白(CRP)升高。85%病例单独使用大环内酯类(红霉素或阿奇霉素)抗感染,15%病例联合使用头孢类抗生素,疗程2~3周。喘息严重或发展迅速的MPP使用甲泼尼龙或氢化可考的松琥珀酸钠。全部病例均使用布地奈德雾化吸入,时间7 d~3个月。结论婴幼儿MPP的发病率高,好发年龄明显提前。血清MP-IgM抗体检测是诊断婴幼儿MPP的主要手段。采用大环内酯类序贯治疗效果好。雾化吸入糖皮质激素可减轻MP感染引起的喘息发作。
出处 《临床军医杂志》 CAS 2013年第4期423-424,共2页 Clinical Journal of Medical Officers
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  • 1Baer G,Engelcke G, Abele-Hom M, et al. Role of Chlamydiapneumoniae and Mycoplasma pneumoniae ascausative agents ofcommunity-acquired pneumoniae in hospitalized children and ad-olescents[ J]. Eur J Clin Microbiol Infect Dis, 2003 , 22 ( 12 ):742 -745.
  • 2Maltezou HC,La-Scola B,Astra H,et al. Mycoplasma pneumon-iae and Legionella pneumophila in community-acquired lower re-spiratory tract infections among hospitalized children: diagnosis byreal time PCR [ J] . Scand J Infect Dis,2004,36(9) : 639 - 642.
  • 3赵顺英.肺炎支原体感染的临床表现和肺外并发症[J].实用儿科临床杂志,2007,22(4):249-250. 被引量:116
  • 4张莹,赵顺英.婴幼儿肺炎支原体肺炎79例临床分析[J].临床儿科杂志,2011,29(8):720-723. 被引量:43
  • 5严永东,黄莉,朱灿红,骆亚丽,王宇清,陈正荣,王美娟,周卫芳,季伟.儿童重症支原体肺炎的临床分析[J].苏州大学学报(医学版),2011,31(5):853-855. 被引量:9
  • 6Hansbro PM, Beagley KW, Horvat JC, et al. ole of atypical bac-terial infection of the lung in predisposition/protection of asthma[J]. Pharmacol Ther,2004 ,101 (3 ) :193 -210.
  • 7Matsuoka M,Narita M,Okazaki N,et al. Characterization and mo-lecular analysis of macrolide-resistant Mycoplasma pneumoniaeclinical isolates obtained in Japan[ J]. Antim Agents Ch,2004,48(12) :4624 -4630.

二级参考文献34

  • 1胡亚美,江载芳.诸福棠实用儿科学[M].7版.北京:人民卫生出版社,2008:2138.
  • 2Tamura A,Matsubara K,Tanaka T,et al. Methylprednisolo- ne pulse therapy for refractory mycoplasma pneumoniae pneumonia in children [ J ]. J Infect, 2008,57 ( 3 ) : 223 - 228.
  • 3Kim NH, Lee JA, Eun BW, et al. Comparison of poly- merase chain reaction and the indirect particle agglutinatio- nantibody test for the diagnosis of mycoplasma pneumoniae pneumonia in children during two outbreaks [ J ]. Pediatr Infect Dis J, 2007,26 (10) : 897 - 903.
  • 4Leong MA,Nachajon R,Ruchelli E,et al.Bronchitis obliterans due to Mycoplasma pneumonia[J].Pediatr Pulmonol,1997,23(5):375-381.
  • 5Waites KB,Talkington DF.Mycoplasma pneumoniae and its role as a human pathogen[J].Clin Microbiol Rev,2004,17(4):697-728.
  • 6Guleria R,Nisar N,Chawla TC,et al.Mycoplasma pneumoniae and central nervous system complications:A review[J].J Lab Clin Med,2005,146(2):55-63.
  • 7Tanir G,Aydemir C,Yilmaz D,et al.Internal carotid artery occlusion associated with Mycoplas pneumoniae infection in a child[J].Turk J Pe-diatr,2006,48(2):166-171.
  • 8Daxboeck F,Blacky A,Seidl R,et al.Diagnosis,treatment,and prognosis of Mycoplas pneumoniae childhood encephalitis:Systematic review of 58 cases[J].J Child Neurol,2004,19 (11):865-871.
  • 9Bruch LA,Jefferson RJ,Pike MG,et al.Mycoplasma pneumoniae infection,meningoencephali and hemophagocytosis[J].Pediatr Neurol,2001,25(1):67-70.
  • 10Said MH,Layani MP,Colon S,et al.Mycoplasma pneumoniae associated nephritis in children[J].Pediatr Nephrol,1999,13(1):39-44.

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