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IL-27双向调节T细胞研究进展 被引量:3

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摘要 白介素27(Interleukin-27,IL-27)是2002年Pflanz等发现并命名的一种新型IL-12家族细胞因子,对不同类型免疫细胞具有重要调控作用。早期认为IL-27在Th1细胞免疫应答中发挥作用,随着研究的不断深入,发现IL-27不仅对Th1、Th2和Th17亚群具有广泛调节作用,
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2013年第4期430-433,共4页 Chinese Journal of Immunology
基金 教育部博士点新教师基金课题(No.20101323120004) 河北省自然科学基金(No.H2012206135) 国家自然科学基金(No.81201607)资助
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同被引文献20

  • 1Kuo A, Gish R. Chronic hepatitis B infection[J]. Clin Liver Dis, 2012, 16 (2) : 347 -369..
  • 2Wang HL, Zhang HY, Zhai ZL, et al. The correlation between hep- atitis B virus infection and IL- 27 [ J]. Biomed Mater Eng, 2012, 22(1 -3) : 187 -193.
  • 3Kao JT, Lai HC, Tsai SM, et al. Rather than interleukin - 27, in- terleukin- 6 expresses positive correlation with liver severity in na? ve hepatitis B infection patients[J]. Liver Int, 2012, 32 (6) : 928 - 936.
  • 4Zhu C, Zhang R, Liu L, et al. Hepatitis B virus enhances interleu- kin- 27 expression both in vivo and in vitro [ J]. Clin hnmunol, 2009, 131(1) : 92 -97.
  • 5Yoshida H, Hamano S, Senaldi G, et al. WSX - 1 is required for the initiation of Thl responses and resistance to L. major infection [J]. Immunity, 2001, 15 (4) : 569 -578.
  • 6Neufert C, Becker C, Wirtz S, et al. IL - 27 controls the develop- ment of inducible regulatory T cells and Thl7 cells via differential effects on STAT1 [J]. Eur J Irnmunol, 2007, 37 (7) : 1809 - 1816.
  • 7Amadi -Obi A, Yu CR, Liu X, et al. Thl7 cells contribute to u- veitis and scleritis and are expanded by IL- 2 and inhibited by Ⅱ - 27/STATl[J]. Nat Med, 2007, 13 (6) : 711 -718.
  • 8张丽丽,左维泽.血清HBeAg阴性慢乙肝患者血清IL-27的检测及其意义[J].临床肝胆病杂志,2009,25(5):334-335. 被引量:2
  • 9尉艳霞,童朝晖,龚娟妮,王臻,王晓娟,徐莉莉,伍燕兵,李红杰,王辰.腺苷脱氨酶诊断结核性胸膜炎价值的再评价[J].中华结核和呼吸杂志,2010,33(4):273-275. 被引量:83
  • 10粱雪松,李成忠,刘亚允,范文瀚,尹伟,徐浩,万谟彬.调节性T细胞和辅助性T细胞17的平衡变化在慢性乙型肝炎病毒感染中的作用[J].中华传染病杂志,2011,39(10):605-610. 被引量:8

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