摘要
生物制剂是近年来在临床使用的一种基于基因工程的新型治疗药物。其中,依那西普、英夫利昔单抗、阿达木单抗及利妥昔单抗等,广泛应用于风湿性疾病的治疗,具有广阔的应用前景。目前,生物制剂对风湿性疾病的育龄妇女在妊娠期和哺乳期的影响,尚缺乏大样本量的双盲、随机对照试验。笔者拟就相关生物制剂在妊娠期和哺乳期风湿性疾病患者中的应用,综述如下。
Biological agents are a kind of new therapeutic drugs which based on genetic engineering for treating rheumatism in recent years, with a broad of application prospects in rheumatism. But the impact of biological agents on childbearing-age women during pregnancy and lactation, is still short of large sample size randomized controlled trials. This article focus on related literatures about the application of biological agents during pregnancy and lactation.
出处
《中华妇幼临床医学杂志(电子版)》
CAS
2013年第2期217-219,共3页
Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)
基金
国家自然科学基金面上项目(81273286)~~
关键词
生物制剂
妊娠
风湿性疾病
biological agents
pregnancy
rheumatism