机械通气过程中镇痛镇静及肌肉松弛药物的合理应用
被引量:3
摘要
镇静技术的规范实施为最大限度地发挥机械通气的优势提供了基础和保障,有大样本的RCT研究结果证实了镇静给患者带来的益处01-23,2006年中华医学会重症医学分会出台了重症加强治疗病房患者镇痛和镇静治疗指南,旨在引导镇静镇痛技术的合理化和规范化。但有调查结果显示指南的依从性并不乐观。另外镇静实施不当亦会增加机械通气时间、谵妄、长期认知功能障碍,甚至死亡。
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
2013年第4期315-316,共2页
Chinese Journal of Tuberculosis and Respiratory Diseases
参考文献19
-
1Schweickert WD, Gehlbach BK, Pohlman AS, et al. Dailyinterruptions of sedative infusions and complications of critical illness in mechanically ventilated patient. Crit Care Med, 2004, 32 : 1272-1276.
-
2Girard TD, Kress JP, Fuchs BD, et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial) : a randomised controlled trial. Lancet, 2008, 371:126-134.
-
3Bair N, Bobek MB, Hoffman-Hog L, et al. Introduction of sedative, analgesic and neuromuscular blocking agent guidelines in a medical intensive care unit: physician and nurse adherence. Crit Care Med, 2000, 28:707-713.
-
4Botha J, LeBlanc V. The state of sedation in the nation : results of an Australian survey. Crit Care Resuscitation, 2005, 7:92-96.
-
5Egerod I, Christensen BV, Johansen L. Trends in sedation practices in Danish intensive care units in 2003 : a national survey. Intensive Care Med, 2006, 32:60-66.
-
6Guttormson JL, Chlan L, Weinert C, et al. Factors influencing nurse sedation practices with mechanically ventilated patients: a U.S. national survey. Intensive Crit Care Nuts, 2010, 26:44-50.
-
7Martin J, Franck M, Sigel S, et al. Changes in sedation management in German intensive care units between 2002 and 2006: a national follow-up survey. Crit Care, 2007, 11 :R124.
-
8Pandharipande P, Shintani A, Peterson J, et al. Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients. Anesthesiology, 2006, 104:21-26.
-
9Kress JP,Pohlman AS,O' Connor MF, el al. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med, 2000, 342 : 1471-1477.
-
10Ma P, Liu J, Xi X, et al. Practice of sedation and the perception of discomfort during mechanical ventilation in Chinese intensive care units. Crit Care, 2010, 25:451-457.
二级参考文献19
-
1Jacobi J, Fraser GL, Coursiu DB, et al. Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult. Crit Care Med,2002,30: 119-141.
-
2Qiao H, Sanders RD, Ma D, et al. Sedation improves early outcome in severely septic Sprague Dawley rats. Crit Care, 2009,13:R136.
-
3Sanders RD, Hussell T, Maze M. Sedation & immunomodulation. Anesthesiol Clin, 2011,29 : 687-706.
-
4Arroliga AC, Thompson BT, Ancukiewicz M, et al. Use of sedatives, opioids,and neuromuscular bilking agents in patients with acute lung injury amd acute respiratory distress syndrome. Crit Care Med, 2008,36: 1083-1088.
-
5Carlon GC, Combs A. Role of sedation and analgesia in mechanical ventilation. Crit Care Med, 2008,36 : 1366-1367.
-
6Jackson DL,Proudfoot CW,Cann KF,et aL The incidence of sub-optimal sedation in the ICU: a systematic review. Crit Care, 2009,13 : R204.
-
7Strcm T, Martinussen T, Toft P. A protocol of no sedation for critically ill patients receiving mechanical ventilation:a randomised trial. Lancet, 2010,375:475-480.
-
8van de Leur JP,van der Schans CP,Loef BG,et al.Discomfort and factual recollection in intensive care unit patients. Crit Care, 2004,8 : R467-473.
-
9Sessler CN, Grap MJ, Ramsay MA. Evaluating and monitoring analgesia and sedation in the intensive care unit. Crit Care, 2008,12 Suppl 3 : S2.
-
10Payen JF, Chanques G, Mantz J, et al.Current practices in sedation and analgesia for mechanically ventilated critically ill patients: a prospective muhicenter patient-based study. Anesthesiology, 2007,106 : 657-695.
共引文献14
-
1承韶晖,潘爱军,陈晓蓉,傅先明,钱若兵.重症监护病房患者谵妄发生率与识别率的现状[J].中国危重病急救医学,2012,24(8):493-494. 被引量:34
-
2刘坤彬,王东浩,马赟,夏睿.瑞芬太尼在重症监护病房机械通气患者镇痛镇静中的应用研究[J].中华危重病急救医学,2013,25(3):167-170. 被引量:32
-
3徐安忆,洪广亮,赵光举,吴斌,邱俏檬,卢中秋.丙泊酚与咪达唑仑对急诊危重病机械通气患者镇静效果的比较研究[J].中华危重病急救医学,2013,25(6):356-359. 被引量:52
-
4杨宏富,孙荣青,常银江,付云,李保林,秦秉玉,芦乙滨,焦宪法,张振平,孙立冬,刘小军,胡亚兰,毛峥嵘.舒芬太尼对重症监护病房危重患者镇痛/镇静治疗的多中心随机对照临床研究[J].中华危重病急救医学,2014,26(2):94-100. 被引量:34
-
5柳舟,董卫国,余追,张亮,姚兰,候果,谢文杰.舒芬太尼与芬太尼对重症患者机械通气血流动力学的影响[J].海南医学,2019,30(1):115-120. 被引量:8
-
6杜志安,胡占升,孙美娜.三种药物联合异丙酚镇痛镇静对ICU内机械通气患者的疗效对比[J].医学与哲学(B),2015,36(8):27-29. 被引量:13
-
7吕杰,刘丹,安友仲,冯艺.以瑞芬太尼镇痛为基础的镇静治疗对危重患者谵妄发生的影响[J].中华危重病急救医学,2015,27(10):845-849. 被引量:13
-
8王伟,杨万杰,冯庆国,赵雪峰,魏凯,李昶,滕洪云.不同镇痛药物对老年术后机械通气患者血流动力学的影响[J].中华危重病急救医学,2015,27(10):853-855. 被引量:18
-
9郑文涛,孙振棣,刘振吉.右美托咪啶与咪达唑仑对于酗酒患者全身麻醉术后镇静的比较研究[J].中国医师进修杂志,2015,38(12):909-912. 被引量:7
-
10李敏雄,余庆华,蔡金亮,何小欢,马俊.奋乃静在重症监护病房患者镇静中的应用价值[J].山西医药杂志,2016,45(23):2765-2766. 被引量:1
同被引文献26
-
1机械通气临床应用指南(2006)[J].中国危重病急救医学,2007,19(2):65-72. 被引量:871
-
2Mannam P,Siegel MD.Analytic review:management of lifethreatening asthma in adults[J].J Intensive Care Med,2010,25:3-15.
-
3Berg KM,Clardy P,Donnino MW.Noninvasive ventilation for acute respiratory failure:a review of the literature and current guidelines[J].Intern Emerg Med,2012,7:539-545.
-
4Brenner B,Corbridge T,Kazzi A.Intubation and mechanical ventilation of the asthmatic patient in respiratory failure[J].J Allergy Clin Immunol,2009,124:S19-S28.
-
5Medoff BD.Invasive and noninvasive ventilation in patients with asthma[J].Respir Care,2008,53:740-748.
-
6Schauer SG,Cuenca PJ,Johnson JJ,et al.Management of acute asthma in the emergency department[J].Emerg Med Pract,2013,15:1-28.
-
7RANIERI VM,RUBENFELD GD,THOMPSON BT,et al.Aeute respi- ratory distress syndrome: the Berlin Definition[J].JAMA,2012,307(23): 2526-2533.
-
8RAMSAY MA,SAVEGE TM,SIMPSON BR,et al.Controlled sedation with alphaxalone-alphadolone[J].Br Med J,1974,2(5920):656-659.
-
9许峰.机械通气中镇静镇痛治疗策略[J].中国实用儿科杂志,2010,25(2):122-122. 被引量:7
-
10刘京涛,马朋林.重症医学科内镇痛和镇静治疗的安全性[J].中华内科杂志,2011,50(10):812-814. 被引量:32
引证文献3
-
1金宇,戴山林.机械通气治疗支气管哮喘的生理学基础与策略[J].中华结核和呼吸杂志,2014,37(7):549-551. 被引量:18
-
2王铎,刘波.镇静评分与中重度急性呼吸窘迫综合征患者临床预后的相关性分析[J].临床医学研究与实践,2016,1(22):27-29. 被引量:2
-
3陆宁,陈跃华,覃鸿发,林艳荣.肌松剂对有创机械通气的艾滋病合并肺孢子菌肺炎患者的疗效评价[J].解放军医学院学报,2018,39(10):866-869. 被引量:4
二级引证文献24
-
1戴山林,孔辉,金宇.肌松剂在危重症哮喘机械通气中的疗效观察[J].南京医科大学学报(自然科学版),2015,35(2):218-221. 被引量:4
-
2易震南,蔡欣,黎月秋,伍俊,黎东明.经支气管镜黏膜活检及灌洗在RICU多药耐药菌定植与感染的鉴定评价[J].中华医院感染学杂志,2015,25(12):2664-2666. 被引量:4
-
3代涛.无创通气治疗急性重症支气管哮喘的效果研究[J].中国卫生工程学,2016,15(6):589-591. 被引量:2
-
4纳建荣,马宣.大剂量皮质激素辅助治疗重症哮喘的疗效观察[J].临床肺科杂志,2017,22(2):284-287. 被引量:11
-
5肖昌玉,张虹,袁艺.BiPAP无创通气用于急诊治疗重度哮喘对患者肺功能的影响情况分析[J].临床急诊杂志,2017,18(1):48-50. 被引量:11
-
6檀月芳.用机械通气术治疗重症哮喘的效果观察[J].当代医药论丛,2017,15(5):21-22.
-
7姚炳华,徐凤玲.关于“三凹征”的疑问[J].中华结核和呼吸杂志,2017,40(5):399-399.
-
8马春香,孙媛.院前640例过度换气综合征患者临床分析[J].现代医药卫生,2017,33(B12):60-61. 被引量:2
-
9魏志明,许勤,张志刚.呼吸重症监护病房多药耐药菌定植与感染的临床鉴定分析[J].中国病原生物学杂志,2018,13(8):903-906. 被引量:10
-
10杨雅瑾,宋宏宾,费燕,谢婷,张耀亭.大剂量硫酸镁治疗重症哮喘的疗效观察[J].临床肺科杂志,2018,23(12):2187-2190. 被引量:3
-
1马红,张丽萍,郑晓燕,袁开明.丙泊酚联合咪达唑仑在先天性心脏病患儿术后的镇静研究[J].中国临床药理学杂志,2015,31(24):2378-2380. 被引量:7
-
2李亭雨,沈锋,白霖果,鲁文婉.机械通气联合镇痛镇静救治恶性心律失常并急性左心衰1例[J].贵阳医学院学报,2012,37(5):580-580. 被引量:2
-
3曹朝阳,雷晚红,丁治强.镇痛镇静用于高血压脑出血疗效观察[J].湖北科技学院学报(医学版),2016,30(1):35-36. 被引量:6
-
4JanetRoloff,王福彭.肌肉减少症:新认识的疾病[J].世界科学,1997(5):19-20. 被引量:1
-
5杨伟.麻醉技术在救治重症肺炎合并急性呼吸窘迫综合征患者中的应用[J].中国基层医药,2012,19(1):136-137. 被引量:1
-
6邢群智,孙丽霞,习红丽.电子胃镜检查中应用芬太尼50例效果观察[J].山东医药,2004,44(33):42-42.
-
7盂庆义.他为何排尿时会晕厥?[J].大众健康,2012(11):44-45.
-
8李凡民.ARDS患者镇痛镇静状态下呼吸力学改变的研究[J].中华全科医学,2014,12(10):1596-1597. 被引量:5
-
9庄明增.镇痛镇静治疗对ICU外伤性高颅压患者颅内压及疗效影响[J].中国实用医药,2014,9(34):146-147. 被引量:3
-
10齐昭义,罗宗荣,赵永进,贾英杰,解智超,丁淑梅,于晓荣.严重烧伤后手术麻醉心跳骤停复苏一例[J].中华烧伤杂志,2009,25(3):206-206.