摘要
目的:探讨多西他赛联合奥沙利铂和替吉奥胶囊方案治疗晚期胃癌的临床疗效及不良反应。方法:28例晚期胃癌患者采用多西他赛+奥沙利铂+吉奥胶囊联合化疗,治疗2周期后进行疗效评价。结果:经过治疗,有2例完全缓解(7.1%),11例部分缓解(39.3%),总有效率46.4%。主要毒副反应为骨髓抑制和消化道反应。结论:多西他赛联合奥沙利铂和替吉奥方案治疗晚期胃癌的近期疗效较好,不良反应可以耐受,可以提高患者的依从性。
Objective： To investigate the therapeutic effect and adverse drug reactions of chemotherapy of docetaxel combined with oxaliplatin and gimeracil in the treatment of advanced gastric cancer.Methods： 28 cases of advanced gastric cancer were treated with docetaxel, oxaliplatin and glmeracil chemotherapy, the efficacy was evaluated after 2 cycles.Results： After treatment, there are two cases of complete remission （7.1%）, 11 cases of partial remission （39.3%）, the total efficiency of 46.4%. The main toxicities were myelosupprcssion and gastrointestinal reactions.Conclusion： Docetaxel combined with oxallplatin and gimeracil is effective and tolerable in the treatment of advanced gastric cancer, meanwhile, it can improve compliance of patients.
出处
《中外医学研究》
2013年第11期27-28,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
胃癌
多西他赛
奥沙利铂
替吉奥
化疗
Gastric cancer
Docetaxel
oxaliplatin
Gimcracil
Chemotherapy
