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小细胞肺癌治疗进展 被引量:10

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摘要 小细胞肺癌(small cell lung cancer,SCLC)大约占到原发肺癌的15%,药物治疗近30年没有大的变化。尽管几十年来有大量的生物学和临床研究,但是目前已经确立的小细胞肺癌的治疗方法是存在着公认的不足的。虽然一些已完成的随机研究进一步确定了有效的治疗策略,如最佳的治疗药物或治疗时间,最合适的剂量和放射治疗的时机,以及为临床实践提供更可靠的询证医学证据,不幸的是这些试验的结论多数是相反的,所以需要对这些试验进行Meta分析以求对个别情况给出清晰的临床治疗策略。本文对目前已有的主要Meta分析结果进行综述。
作者 张力
出处 《癌症进展》 2013年第2期99-105,共7页 Oncology Progress
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  • 1Pelayo Alvarez M, Gallego Rubio O, Bonfi11 Cosp X, et al. Chemotherapy versus best supportive care for extensive small cell lung cancer [ DB ]. Cochrane Database Syst Rev, 2009, 7 (4): CD001990.
  • 2Tan WW, Maghfoor I, Harris JE. Small cell Lung Cancer [J/OL]. [2012 - 06 - 10]. http: //emedicine. med- scape, corn/article/280104-overview.
  • 3Pujol JL, Carestia L, Daurs JP. Is there a case for cispla- tin in the treatment of small-cell lung cancer A meta-analy- sis of randomized trials of a cisplatincontaining regimen ver- sus a regimen without this alkylating agent [ J ]. Br J Cancer, 2000, 83 ( 1 ) : 8 - 15.
  • 4Amarasena IU, Wahers JA, Wood-Baker R, et al. Plati- num versus non-platinum chemotherapy regimens for small cell lung cancer [ DB ]. Cochrane Database Syst Rev, 2008, 8 (4): CD006849.
  • 5Rossi A, Di Maio M, Chiodini P, et al. Carboplatin- or cispl- atin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data [Jl. J Clin Oncol, 2012, 30 (14): 1692 -1698.
  • 6Mascaux C, Paesmans M, Berghmans T, et al. A system- atic review of the role of etoposide and cisplatin in the chemotherapy of small cell lung cancer with methodology assessment and meta-analysis [ J]. Lung Cancer, 2000, 30 (1):23-36.
  • 7Shao N, Jin S, Zhu W. An updated meta-analysis of ran- domized controlled trials comparing irinotecan/ platinum with etoposide/ platinum in patients with previously un- treated extensive-stage small cell lung cancer [J]. J Tho- rac Oncol, 2012, 7 (2):470-472.
  • 8Hanna N, Bunn Jr PA, Langer C, et al. Randomized phase ]11 trial comparing irinotecan/cisplatin with etopo- side/cisplatin in patients with previously untreated exten- sive-stage disease small-cell lung cancer [ J]. J Clin On- col, 2006, 24 (13):2038 -2043.
  • 9Lara Jr PN, Natale R, Crowley J, et al. Phase m trial of irinoteean/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and phar- macogenomic results from SWOG S0124 [J]. J Clin On- col, 2009, 27 (15) : 2530 - 2535.
  • 10Warde P, Payne D. Does thoracic irradiation improve sur- vival and local control in limited-stage small-cell carcinoma of the lung A recta-analysis [J]. J Clin Oncol, 1992, 10(6) : 890 - 895.

同被引文献121

  • 1曹子昂.2014第一版NCCN小细胞肺癌治疗指南解读[J].中国医学前沿杂志(电子版),2013,5(12):79-81. 被引量:26
  • 2李兰芳,王华庆.小细胞肺癌的二线化疗及研究进展[J].肿瘤研究与临床,2006,18(6):424-426. 被引量:15
  • 3曾益新.肿瘤学[M].第3版.北京:人民卫生出版社,2012:597-598.
  • 4孙燕,石远凯.临床肿瘤内科手册[M].第5版.北京:人民卫生出版社,2012:123-124.
  • 5Buccheri G1, Ferrigno D, Tamburini M. Karnofsky and ECOG performance status scoring in lung cancer: a prospective, longitu- dinal study of 536 patients from a single institution [ J]. 1996,32A (7) :1135 - 1141.
  • 6Kallianos A, Rapti A, Zarogoulidis PA, et al. Therapeutic procedure in small ceil lung cancer[J]. J Thorac Dis, 2013, 5(4):$420-$424.
  • 7Lara PN, Natale R, Crowley J, et al. Phase IU trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124[J]. J Clin Oncol, 2009,27(15):2530-2535.
  • 8Okamoto H, Watanabe K, Kunikane H, et al. Randomised phase III trial of carboplatin plus etoposide vs split doses of cisplatin plus etoposide in elderly or poor-risk patients with extensive disease small-cell lung cancer. JCOG 9702[J]. Br J Cancer, 2007, 97(2):162-169.
  • 9RossiA, Martelli O, Di Maio M. Treatment of patients with small-cell lung cancer: from meta-analyses to clinical practice[J]. Cancer Treat Rev, 2013, 39(5):498-506.
  • 10Moore AM, Einhorn LH, Estes D, et al. Gefitinib in patients with chemo-sensitive and chemo-refractory relapsed small cell cancers: a Hoosier Oncology Group phase II trial[J]. Lung Cancer, 2006, 52(1):93-97.

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