摘要
为探讨不同手术方法治疗直肠癌对患者术后生活质量及免疫功能的影响，将60例直肠癌患者随机分为观察组和对照组，每组30例。观察组采用腹腔镜直肠癌根治术治疗，对照组采用传统开腹直肠癌根治术治疗，比较两组患者的手术效果、术后生活质量及免疫功能的变化。结果显示，两组的手术时间差异无统计学意义（P〉0．05）。观察组的术中出血量、排气时间、进食时间、住院时间均显著少于或短于对照组（P〈0．05）。观察组术后在躯体功能、心理功能、社会功能、物质生活状态方面的生活质量评分显著高于对照组（P〈0．05）。观察组术后7d的免疫学指标CD4^＋、CD4^＋／CD8^＋、IgM、IgG的含量均显著高于对照组（P〈0．05）。结果表明，与开腹手术相比，腹腔镜手术不但具有微创手术的优点，而且在患者术后生存质量及保护患者的免疫功能方面具有优势。
In order to explore the influence of different surgical procedures on the quality of life and im-mune function in patients after the surgery for rectal cancer,60 cases were randomly divided into observa-tion group and control group, 30 cases for each. The former underwent laparoscopic radical resection and the latter conventional open radical resection. Both groups were compared in clinical efficacy, postoperative quality of life and immune function. The results showed that there was no significant difference between the two groups in surgery time （ P 〉0.05） ;intraoperative bleeding volume,time for flatus and eating,and hos-pital stay were significantly less or shorter in observation group than in control group（ P 〈0.05）;the in-dex scores of postoperative quality of life including physical function, psychological function, social function and living conditions were significantly higher in observation group than in control group（ P 〈0.05） ;the levels of immune indicator including CD4^＋ , CD4^＋/CD8^＋ , IgM and IgG were obviously higher at seven days after surgery in observation group than in control group（ P 〈0, 05）. It is concluded that compared with open surgery, laparoscopic surgery is minimally invasive and also has advantages in protecting patients quality of survival and immune function.
出处
《中国肛肠病杂志》
2013年第3期12-14,共3页
Chinese Journal of Coloproctology
关键词
直肠癌
生活质量
免疫功能
腹腔镜
开腹手术
Rectal cancer
Quality of life
Immune function
Laparoscope
Open surgery
