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去白细胞输血降低非溶血性发热反应的临床应用 被引量:6

Clinical application of transfusion of leukocyte filtration blood prevent febrile nonhemolytic transfusion reactions
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摘要 目的:评价临床输注去白细胞红细胞悬液和单采血小板降低非溶血性发热性输血反应(FNHTR)的效果。方法:150例输注去白细胞血液制剂(红细胞悬液和血小板)的患者为观察组,同期150例输注非去白细胞同类血液制剂的患者为对照组,观察2组FNHTR的发生率。结果:观察组和对照组输注红细胞悬液后FNHTR分别为3例(3%)和18例(18%);观察组和对照组输注血小板后FNHTR分别为4例(8%)和15例(30%),2组比较差异有统计学意义(P<0.01)。结论:去白细胞输血可有效防止或降低FNHTR的发生,对多次输血治疗的患者效果尤佳。 Objective:To assess the clinical efficiency of preventing febrile nonhemolytic transtusion reactions (FNHTR) with transfusion of leukocyte filtration RBC and platelet concentrates. Method: 150 patients were selected to receive leukocyte titration blood products (RBC and platelet concentrates). Anther 150 similar patients were selected to receive non-filtered blood products. The incidence rates of FNHTR in all patients were investigated. Resuit:There was 3 and 18 patients with FNHTR occurred separately in filtrated and non-filtrated RBC concentra tions. The incidence of FNHTR was separately 3 %and 18 %. There was 4 and 15 patients with FNHTR occurred separately in filtrated and non-filtrated platelet concentrations. The incidence of FNHTR was separately 8% and 30 %. Conclusion: Leukocyte filtration of RBC and platelet concentrates could reduce FNHTR in blood transfusion, especial in procedure of multiple transfusion.
出处 《临床血液学杂志(输血与检验)》 CAS 2013年第2期227-228,231,共3页 Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词 去白细胞 输血 非溶血性发热反应 leukocyte filtration blood transfusion febrile nonhemolytic transfusion reactions
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