摘要
目的:对3例RhD阴性产妇所育的RhD阳性新生儿因D抗原遮蔽造成假阴性现象,进一步进行血型血清学检测及分析。方法:采用血型血清学方法检测新生儿及其母亲、父亲血型抗原、抗体。结果:新生儿血型分别为O,CcDEe、B,CCDEe、A,CcDEe;其母亲分别为O,ccdee、B,ccdee、AB,ccdee;其父亲分别为:O,CcDEe、O,CCDEe、A,CcDEe;新生儿直接抗球蛋白试验分别为:3+、3+、3+。对新生儿进行RhD血型检测时,试管法观察结果未见凝集,易误判为RhD阴性。结论:通过血型血清学检测该3例患儿RhD抗原为阳性,并由Rh系统IgG抗D引起的新生儿溶血病,为新生儿能得到及时治疗提供实验室依据。
Objective：To further test and analyze the blood group serology of three RhD^positive newborns due to the D antigen masking caused false negative phenomenon,whose mothers antigen blood group serology test was negative. Method：The blood group antigens and antibodies of newborns and their parents were detected by Serological techniques. Result： The neonatal blood types were O, CcDEe ; B, CCDEe and A, CcDEe, respectively ; their mothers were O, ccdee ; B ccdee and AB, ccdee, respectively ; fathers were ： O, CeDEe ; O CCDEe and A, CeDEe, respective- ly. The results of newborn direct antiglobulin test were 3 ＋ ,3 ＋ and 3 ＋, respectively. During RhD detection for newborns,there was no agglutination by tube method,easily mistaken as RhD negative. Conclusion：The 3 newborns RhD antigen blood group serology test was positive,and the hemolytic disease of newborns was caused by the Rh System IgG anti-D. These data would provide laboratory basis for newborn timely treatment.
出处
《临床血液学杂志（输血与检验）》
CAS
2013年第2期219-221,共3页
Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
关键词
血型RhD
新生儿溶血
遮蔽现象
假阴性
鉴定与分析
Blood type RhD
hemolytic disease of newborns
shadowing phenomenon
{alse negative
identifica-tion and analysis
