摘要
目的:探讨军人失眠症患者治疗前后P300和MMSE量表评分的变化。方法:收集符合CCMD-3失眠症诊断标准的军人失眠症患者48例作为研究组,50名正常官兵作为对照组。应用简易精神状态量表(MMSE)进行认知功能评分,应用美国NicoletBravo脑诱发电位仪进行P300检测。结果:研究组MMSE总分(25.37±1.43)较对照组(28.63±1.62)显著降低(P<0.05);研究组P300潜伏期(332.34±25.92)ms较对照组(310.46±22.58)ms显著延长(P<0.05)。军人失眠症患者经4周治疗后P300潜伏期缩短,MMSE评分显著改善。结论:军人失眠症患者认知功能较正常人明显减退,经治疗后认知功能的改善与临床症状的缓解相关。
Objective： To explore the change of P300 and MMSE assessment of soldiers with insomnia in pre and post-treatment. Method：Forty-eight soldiers with insomnia as research group and fifty normal ranks as the control group were measured with mini-mental state examination（MMSE）and recorded with P300. Results：There were significant differences in MMSE scores between the two groups[（25.37±1.43）,（28.63±1.62）,P0.05].The latency of P300 of soldiers with insomnia （332.34±25.92）ms were significantly different from normal controls[（310.46±22.58）ms,P0.05].After 4 weeks＇ treatment,the scores of MMSE and latencies of P300 of the soldiers with insomnia were significantly improved（P0.05）. Conclusion： The cognitive function of soldiers with insomnia drop obviously compared with the control group and improves after treatment.The improvement correlates with potential symptoms remission.
出处
《临床精神医学杂志》
2013年第2期119-120,共2页
Journal of Clinical Psychiatry
