摘要
目的探讨肝门部胆管癌术后的预后因素。方法回顾性分析65例肝门部胆管癌患者临床资料,分析影响肝门部胆管癌预后的因素。结果不同手术方式术后1 a生存率、2 a生存率及中位生存期比较差异有统计学意义(P<0.05)。单因素分析发现,手术方式、淋巴结转移情况、周围血管浸润情况、病理组织分化程度和肿瘤TNM分期是影响预后的因素;COX模型多因素分析结果显示,手术方式、淋巴结转移情况和肿瘤病理组织分化程度是影响预后的独立因素。结论根治性切除及彻底的淋巴结清扫是改善肝门部胆管癌预后的重要措施。
Objective To investigate the postoperative prognosis factors of hilar cholangiocarcinoma. Methods The clinical data of 65 cases of hilar cholangiocarcinoma were retrospectively analyzed, and the postoperative prognosis factors were analyzed. Results There were significant differences in the 1- and 2- year survival rates and medi- an survivals among the patients treated with different surgical methods （ P 〈 0.05 ）. Univariate analyses showed the surgical method,lymphatic metastasis, peripheral vascular infiltration, staging of pathology and TNM stage were sta- tistically significant prognostic value （ P 〈 0.05 ）. On a multivariate analysis using the COX proportional hazards model, the surgical method, lymphatic metastasis and the staging of pathology were independent prognistic factors. Conclusion Radical excision and lymphadenectomy are the important prognostic factor for hilar cholangiocarcinoma and extended resection improved the prognosis.
出处
《肿瘤基础与临床》
2013年第2期132-134,共3页
journal of basic and clinical oncology
关键词
肝门部胆管癌
外科手术
预后
hilar cholangiocarcinoma
surgical treatment
prognosis
