摘要
目的:溃疡性结肠炎(UC)是一个多病灶点的复杂疾病。愈肠宁方中含黄芪、苦参。黄芪益气健脾,苦参清热燥湿,两药协同使标本兼治,提高药效。方法:通过对治疗UC的文献调研分析,选用恰当的评价方法,对文献进行筛选,并对用药规律进行统计。结果:得到符合标准得文献234篇,统计分析可知,在UC临床治疗中黄芪的用药频率是33.0%,口服占用药途径的72.7%;苦参用药频率为19.7%,灌肠占用药途径的73.9%。从统计的结果得出临床治疗UC的药物和给药方式与愈肠宁方设计思路一致。结论:该设计思路与近20年的UC临床用药实践一致,因此推测该设计研制的制剂安全、有效。
Objective：Ulcerative colitis（UC） is a more complex diseases of the multiple lesions point.In yuchangning prescription,astragalus nourish qi and invigorate spleen.Sophora clear heat and eliminate dampness,The two drugs can treate both principal and secondary aspect of diseas,improve the efficacy.Method：Now through the literature researching to analysis on the treatment of UC,selecte appropriative evaluation methods,to screen of literature.Add up the discipline of mediciation in the literature.Result：received 234 literatures accorded to the standard,from the statistical analysis,in clinical the using of the Astragalus drug frequency is 33.0%,72.7% use oral mode of administration;the using of the Sophora drug frequency is 19.7%,79.3% use enema mode of administration;Derived from the statistical results,the clinical treatment of UC drugs and drug delivery is according with the consistency of design ideas.Conclusion：The design ideas of the studying agree with nearly 20 years of UC clinical medicine practical.So speculate the designed and developed by preparations safe and effective.This conclusion is also consistent with previous studies of this group.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第8期350-354,共5页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家科技部"重大新药创制"科技重大专项"十二五"重大新药创制项目(2012ZX09102201-103)
关键词
溃疡性结肠炎
黄芪
苦参
文献研究
ulcerative colitis
Astragalus
sophora
literature research
