摘要
目的 Essen卒中风险评估(ESRS)体系可准确评估非心源性缺血性脑卒中(IS)复发的风险。本研究立意于探索急性缺血性脑卒中的OCSP分型与ESRS之间的关系。方法①对连续纳入的非心源性IS患者行ESRS评估,将其分为低风险组(ESRS<3分)和高风险组(ESRS≥3分);②OCSP分型:完全前循环卒中(TACI),部分前循环卒中(PACI),腔隙性卒中(LACI)和后循环卒中(POCI)。比较不同ESRS分值组之间OCSP分型的构成。结果纳入的316例非心源性IS患者中低风险组93例(29.4%),高风险组223例(70.6%),动脉粥样硬化性脑梗死患者(AT)161例(50.9%)。PACI者143例(45.3%),LACI者99例(31.3%),POCI者43例(13.6%),TACI者31例(9.8%)。所有患者中,不同OCSP分型在不同ESRS分值组的构成分布在统计学上没有显著性差异(P=0.111);不同OCSP分型在高低风险组间的构成分布在统计学上无显著性差异(P=0.397)。AT患者中,不同ESRS分值组的OCSP分型的分布也没有明显的统计学差异(P=0.817);高、低风险组中的OCSP分型的分布无显著的差异(P=0.885)。结论本研究提示:①非心源性急性缺血性脑卒中的再发风险的大小与其发生的部位可能无关联;②AT的卒中发生部位与再发风险尚无明确的关联性,风险愈高,并不意味着某部位卒中病灶出现的概率就愈高。
Objective ESRS （ Essen stroke risk score） could be used to measure the recurrent risks of acute non-cardiac ischemic stroke. We tried to explore the relationships between subtypes according to OCSP （Oxfordshire community stroke project） and ESRS in these patients. Methods We divided consecutive patients with acute non-cardiac ischemic stroke into group of high risk and low risk, according to if their ESRS was higher than 3 points. We compared the proportion of each OCSP subtype in groups of different ESRS level. We also used modified TOAST system （trial of Org 10172 in acute stroke treatment）to evaluate stroke etiologies. Results We had 316 eligible patients in total, 29.4% of which were brought into low risk group and the rest into high risk group. There were 161 patients with AT （atherothrombosis） according to modified TOAST system. There were 143 patients （45. 3% ） with PACI （partial anterior circulation infarct）, 99 （31. 3%） with LACI （lacunar infarct）, 43 （13. 6%） with POCI （posterior circulation infarct） and 31 with TACI （total anterior circulation infarct）. The proportion of each OCSP subtype in groups of different ESRS level had no significant difference statistically in all patients （P = 0.111 ）. So did in groups of high risk and low risk （P = 0.397）. Among the patients with AT, distribution of OCSP subtypes in groups of different ESRS and different risk had no significant difference statistically （ P = 0. 817, P = 0. 885, respectively）. Conclusions Our study indicated that ESRS of patients with acute non-cardiac ischemic stroke may not be related to their OCSP subtype. It could be interpreted that patients with high recurrent risk would not have a specific location where ischemic lesion happens more often.
出处
《中华脑血管病杂志（电子版）》
2012年第6期15-19,共5页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
