摘要
龙葵素（Solanen）是存在于茄科植物马铃薯中的有毒甾体类糖苷生物碱。成熟的马铃薯中,龙葵素的含量一般为7~10mg/100 g,食用是安全的。当马铃薯由于贮存不当而变绿或发芽时,会产生大量的龙葵素,当龙葵素的含量超过20mg/100 g时,人服用后可能会导致中毒甚至死亡,相关中毒案件时有报道。结合近年来关于马铃薯中有毒成分龙葵素的研究作一综述,总结了龙葵素毒理学、药理学、药代动力学及检测方法,为法医毒理学工作者提供参考。
Solanen, toxic steroidal glycoalkaloid, exists in solanaceous plants such as potato plant.Mature potatos containing 7-10 mg solanen/100g potato is safe for human consumption. Solanen can be rapidly stimulated when potato turns green and sprouted by improper storage. Solanen has been estimated to he toxic in human at doses greater than 20 mg/100g potato. This paper summarizes the current researches on solanen in potato, the toxicology, pharmacology, pharmacokineties and determina-tion of solanen, provides the reference for forensic toxicology workers.
出处
《中国司法鉴定》
2013年第2期35-41,共7页
Chinese Journal of Forensic Sciences
基金
上海市科委资助项目(072512019)
上海市法医学重点实验室(11DZ2271500)
