摘要
2型糖尿病是一种慢性代谢障碍性疾病,呈进行性发展,很难治愈,占糖尿病的90%以上。目前治疗该病的药物有很多,包括传统药物如磺脲类、格列奈类、噻唑烷二酮类、双胍类和α-葡萄糖苷酶抑制剂,以及近些年出现的新作用机制药物如GLP-1受体激动剂、DDP-IV抑制剂和SGLT2抑制剂。对上述各类药物的研究情况进行综述。
Type 2 diabetes is a kind of chronic metabolic disorders and progressive diseases difficult to cure,which is accounting for more than 90% of the diabetes.Currently,there are a lot of drugs for the treatment of type 2 diabetes,including the traditional drugs such as sulfonylureas,glinides,thiazolidinediones,biguanides,and α-glucosidase inhibitor,and drugs with new mechanism developed in recent years,such as GLP-1 receptor agonist,DDP-IV inhibitor,and SGLT2 inhibitors.This article reviewed the research and development of the above types of drugs.
出处
《现代药物与临床》
CAS
2013年第2期108-113,共6页
Drugs & Clinic
