肢体缺血预适应保护远隔组织器官的研究进展
摘要
肢体缺血预适应(LIP)可通过机体某些脏器短暂性的缺血再灌注减轻重要脏器的缺血再灌注损伤,对远隔多脏器的缺血再灌注损伤有一定保护作用,在保护心、肝、脑、脊髓、肺和皮瓣等组织器官的缺血再灌注损伤的研究中倍受关注,有重要的临床价值,且操作简单、廉价,损伤小,应用前景广阔,但其保护作用的机制有待进一步研究。
出处
《海峡预防医学杂志》
CAS
2013年第1期13-15,共3页
Strait Journal of Preventive Medicine
参考文献29
-
1Murry CE, Jennings RB, Reimer KA. Preconditioning with ische- mia: a delay of lethal cell injury in ischemic myocardium[J]. Cir- culation, 1986,74(5) : 1124-1136.
-
2Kharbanda RK, Mortensen UM, White PA, et al. Transient limb ischemia induces remote ischemic preconditioning in vivo[J]. Cir- culation, 2002,106 (23) .. 2881-2883.
-
3Konstantinov IE, Li J, Cheung MM, et al. Remote ischemic pre- conditioning of the recipient reduces myocardial ischemia-reperfu- sion injury of the denervated donor heart via a Katp channel-de- pendent mechanism [ J ]. Transplantation, 2005, 79 ( 12 ) : 1691- 1695.
-
4Shahid M,Tauseef M, Sharma KK, et al. Brief femoral artery is- chaemia provides protection against myocardial ischaemia reper fusion injury in rats: the possible mechanisms[J]. Exp Physiol, 2008,93(8) :954-968.
-
5Kanoria S,Jalan R,Davies NA, et al. Remote ischaemic precondi- tioning of the hind limb reduces experimental liver warm ischae- mia-reperfusion injury[J]. Br J Surg,2006,93(6) :762-768.
-
6Kanoria S, Glantzounis G, Quaglia A, et al. Remote precondition- ing improves hepatic oxygenation after ischaemia reperfusion inju- ry[J]. Transpl Int, 2012,25 (7) : 783-791.
-
7Lai IR, Chang KJ,Chen CF, et al. Transient limb ischemia induces remote preconditioning in liver among rats: the protective role of heme oxygenase-l[-J]. Transplantation,2006,81(9) :1311-1317.
-
8Abu-Amara M, Yang SY, Quaglia A,et al. Nitric oxide is an es- sential mediator of the protective effects of remote ischaemic pre- eonditioning in a mouse model of liver ischaemia/reperfusion inju- ry[J]. Clin Sci (Lond) ,2011,121(6) :257-266.
-
9Abu-Amara M,Yang SY,Quaglia A,et al. Role of endothelial ni- tric oxide synthase in remote isehemie preconditioning of themouse liver[J]. Liver Transpl, 2011,17 ( 5 ) 610-619.
-
10Ren C,Gao X,Steinberg GK,et al. Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning [J]. Neuro- science, 2008,151(4) : 1099-1103.
-
1祁海珍.重症肺炎患者临床救治回顾分析[J].医药论坛杂志,2010,31(22):168-169. 被引量：6
-
2陈林,张琪.脓毒症中细胞自噬的研究现状[J].中国小儿急救医学,2016,23(11):780-783.
-
3李淑娟,娄建石.肢体缺血预适应保护远隔组织器官的应用研究进展[J].中国药理学通报,2006,22(11):1300-1303. 被引量：4
-
4李青,蔡立勉.血管活性肠肽(VIP):抗炎与器官保护的实验研究进展[J].中国医疗前沿,2007,2(12):66-67. 被引量：3
-
5孙宁玲.心脑器官的保护基础是血压充分的达标[J].心血管病学进展,2006,27(5):543-545. 被引量：8
-
6刘芳,徐启勇,叶燕青.肝细胞生长因子与器官保护[J].国际呼吸杂志,2005,25(S1):63-65. 被引量：1
-
7孙宁玲.高血压(5)不同降压药物在降压及器官保护中的评价(续完)[J].中国循环杂志,2008,23(5):324-327. 被引量：3
-
8杨雪,曾思,兰志勋.p38丝裂原活化蛋白激酶信号通路在丙泊酚器官保护中的作用[J].医学综述,2015,21(6):961-964. 被引量：1
-
9孙宁玲.降压达标对器官保护的作用[J].医学与哲学（B）,2006,27(4):24-25.
-
10赵运河,皮鑫,王秀锋.急性脑血管病并发多器官功能障碍45例分析[J].中国实用医药,2012,7(3):75-76. 被引量：4
