摘要
目的评价Tp-Te间期、QTd、QTcd及其组合在预测冠心病恶性心律失常中的价值。方法入选158例确诊冠心病患者,入院时全部予以12导联心电图检查,将患者按照是否发生恶性心律失常(室性心动过速、心室扑动、心室纤颤)分为病例组和对照组,比较两组患者Tp-Te、QTd、QTcd值,计算它们及其组合在预测恶性心律失常中的敏感度、特异性等指标。结果病例组Tp-Te、QTd、QTcd均大于对照组(P<0.01)。Tp-Te在预测恶性心律失常中的价值最高,其次为QTcd,其敏感度、特异性、阳性预测值、阴性预测值分别为88.46%vs 84.62%、92.5%vs 77.5%、92.0%vs 78.6%、89.2%vs 83.8%。Tp-Te与QTcd并、串联未能提高对恶性心律失常的预测能力。结论 与QTd、QTcd相比,Tp-Te是预测冠心病恶性心律失常强有力的指标,尤其当Tp-Te间期>148ms时应积极预防。
Objective To evaluate the value of Tp - Te interval,QTd,QTcd and their combination in predicting malignant arrhythmi- a in coronary heart disease patients. Methods The investigation was conducted in 158 patients diagnosed as coronary heart disease. All the patients were given the 12 leads electrocardiogram check. We divided the patients into case and control groups according to the occur- rence of malignant ventricular arrhythmias （ ventricular tachycardia, ventricular flutter,ventricular fibrillation）. The values of Tp - Te, QTd and QTcd were compared between the two groups. The sensitivities and specificities of Tp - Te, QTd and QTcd and their combination were calculated in predicting malignant arrhythmias. Results The Tp - Te, QTd and QTcd in the case group were greater than the control group （P 〈 0.01 ）. The value of Tp - Te for the prediction of the malignant arrhythmia is the highest, followed by QTcd. The sensitivity, specificity, positive predictive value, negative predictive value of Tp - Te and QTcd were 88.46% vs 84.62% , 92.5% vs 77.5% , 92.0% vs 78.6% , 89.2% vs 83.8%. Parallel or series in Tp - Te and QTcd was not found to improve the prediction capability of malig- nant arrhythmia. Conclusion Compared with QTd and QTcd, the Tp -Te interval is a strong indicator in predicting the malignant ven- tricular arrhvthmia in coronary heart disease. EsDeciallv when the TD- Te interval 〉 148ms.we should vav attention to vrevention.
出处
《医学研究杂志》
2013年第3期94-97,共4页
Journal of Medical Research
基金
温州市科技计划项目(2010S0195)
关键词
Tp—Te间期
QTd恶性心律失常
冠心病
12导联心电图
Tp- Te interval
QT dispersion
Malignant ventricular arrhythmia
Coronary artery disease
Electrocardiogram
