摘要
目的了解河南省既往采供血途径HIV感染者感受到的艾滋病相关歧视与服药依从性等因素之间的关联性。方法对河南省416采供血途径HIV感染者开问卷调查,评估其遭受过歧视的经历及其关联因素,采集静脉血开展CD4+T细胞检测。结果 140人(33.7%)曾遭受过艾滋病相关歧视,24.8%因歧视而不敢或很少串门或去亲戚家,6.3%因遭受歧视而被迫更换治疗医院,9.2%的接受抗病毒治疗者中在最近1个月漏服过药物。Logistic回归分析显示,相对未接受抗病治疗者,接受抗病毒治疗者感受到的艾滋病相关歧视感更低[OR(95%CI)=0.5[0.3～0.8],P<0.001],而未感受到艾滋病相关歧视的抗病毒治疗者比感受到歧视者漏服抗病毒药物的比例更低(OR=0.2,95%CI:0.0～0.1,P<0.001)。尚未发现CD4+T细胞计数与艾滋病歧视之间存在统计学关联性(P>0.05)。结论 抗病毒治疗可降低患者的艾滋病相关歧视感,但歧视问题可导致感染者抗病毒治疗依从性降低,漏服抗病药物的比例显著增加。需加强宣传教育以消除各界对HIV感染者的歧视,提高其生存质量。
Objective To investigate the status of HIV/AIDS related discrimination and its correlation with compliableness in using anti - virus drug among former blood donors. Methods A survey of 416 HIV infected former blood donors was conducted from 2008 to 2009 in Henan province, China. The participants experienced HIV/AIDS related stigma and discrimination year were assessed, and asso- ciation between HIV discrimination and compliableness in using anti - virus drug etc. were analyzed. Blood specimens were drawn from each participant to test of CD4 ＋ T cells counts. Results Totally 140（33.7% ） of participants once experienced HIV/AIDS related dis- crimination, 24.8% was afraid or not dare to visit neighbors/relatives, 6.3 % were forced to changed hospital to treat diseases, and 9.2% of PLWHs who was receiving HAART treated forgot to take ART drugs within the past month. Logistic analysis identified that, HAART treated PLWHs felt significantly lower proportion of discrimination compared with those who was not currently receiving HAART treatment [32.9% vs65.5%, OR（95% CI） =0.5（0.3-0.8）,P〈0.001].And those HAART treated PLWHs who did not experience HIV/ ADIS related discrimination had significantly lower proportion of missing to take HAART drugs than those HAART treated PLWHs who ex- perienced HIV/ADIS related discrimination（ 1.3% vs 45.8% , OR = 0.2, 95 % C1：0.0 - 0.1 ,P 〈 0. 001 ）. CD4 ~ T counts had no statis- tical correlation with discrimination. Conclusion HARRT can decrease the feeling of HIV/AIDS related discrimination, but the suffered HIV/AIDS discrimination may increase the risk of poor compliance for taking HAART drugs. More propaganda and education should be given to the general population and health care system etc. To eliminate their discrimination to PLWH, and to improve PLWHs＇ quality level of life.
出处
《医学研究杂志》
2013年第3期18-20,共3页
Journal of Medical Research
基金
国家"十二五"规划科技重大专项基金资助项目(2012ZX10001006-001-012)
关键词
既往采供血者
艾滋病病毒
歧视
依从性
Formal blood donors
People who lived with HIV（PLWH）
Discrimination
Compliance
