摘要
目的:通过研究老年变应性鼻炎患者年龄分布及变应原阳性率等变化,了解老年变应性鼻炎的发病趋势。方法:回顾性分析2006年至2010年武汉地区294例50～84岁的老年变应性鼻炎患者过敏原点刺试验结果,描述老年变应性鼻炎患者年龄分布及各变应原阳性率随时间变化的临床特征。结果:老年期患者(≥65岁)人数在受试老年患者总人数的比例随时间推移逐渐增加,但差异无统计学意义(P>0.05)。在5年间老年变应性鼻炎患者粉尘螨阳性率为历年最高,其次为屋尘螨,两者的阳性率在5年间差异不具有统计学意义(P>0.05);艾蒿、豚草花粉、真菌I组、真菌II组阳性率改变均具有统计学意义(P<0.05),其中艾蒿、豚草花粉阳性率呈逐年下降趋势,真菌I组、真菌II组阳性率呈上升趋势;多价兽毛阳性率有增长趋势,但差异无统计学意义(P>0.05);春季花粉I组、春季花粉II组阳性率均呈波动性改变,其中春季花粉II组差异具有统计学意义(P<0.05)。结论:老年变应性鼻炎患者人数显示逐年增长趋势,尘螨过敏在老年患者中仍为最为常见的变应原,但无整体人群体现出的增长趋势,真菌阳性检出率呈现显著增长趋势,兽毛过敏有较弱升高倾向。
Objective： To investigate the prevalence trends of allergic rhinitis in elderly by studying the changes of age distribution and the positive rate of common allergens in elderly patients with allergic rhinitis.Methods： The results of skin prick test about 294 cases（aged from 50 to 84 years,from 2006 to 2010） who were diagnosed as allergic rhinitis were assessed,the changes of age distribution and the positive rate of common allergens were explored.Results： The proportion of patients（≥ 65 years） grew steadily,but had no statistical difference（P0.05）.The positive rate of dust mites was the highest in the last five years,the change was not statistical difference（P0.05）;the positive rate of Mugwort,Ragweed pollen,fungal group I and fungi Group II changes were statistically different（P0.05）.There was an upward trend in the first two,and a downward trend in the latter two.The positive rate of multivalent animal hair were grown steadily,but had no statistical significance（P0.05）.The positive rate of the Spring pollen group I,the Spring group II were fluctuant in the last five years,and the difference in the sprung pollen II group was statistically different（P0.05）.Conclusion： A growth trend was shown in the number of elderly patients with allergic rhinitis,dust mite was still the most common allergen,the positive rate of fungal presented a significant growth trend,while the positive rate of animal hair showed a weakly increasing trend.
出处
《现代生物医学进展》
CAS
2013年第5期866-868,871,共4页
Progress in Modern Biomedicine
基金
国家自然科学基金项目(30973280/H1301)
