摘要
目的探讨心力衰竭(HF)患者血浆脑利钠肽(BNP)水平与心功能的关系。方法选择HF患者82例,健康对照组20例,采用免疫荧光法测定血浆BNP水平,用超声心动图测定HF患者左心室射血分数(LVEF)。结果 HF组BNP值显著高于对照组(P<0.01),且BNP水平随着美国纽约心脏病协会(NYHA)分级的增加而升高(P<0.01),而与LVEF呈负相关(r=-0.67,P<0.01)。结论血浆BNP水平可作为HF患者心功能评估的有效生化指标。
Objective To study the relationship between plasma brain natriuretic peptide（BNP） level and the cardiac function in the patients with heart failure（HF）.Methods The plasma level of BNP in 82 patients with HF as the HF group and 20 healthy individuals as the control group were measured by fluoroimmunoassy and the left ventricular ejection fraction（LVEF） was measured by echocardiography.Results Plasma BNP level in the HF group was significantly higher than that in the healthy control group（P0.01）.The BNP level was gradually increased with the increase of the cardiac function classification（NYHA）（P0.01）.There was the negative correlation between BNP level and LVEF（r=-0.67,P0.01）.Conclusion The plasma BNP level can be used as an effective biochemical marker for evaluating the cardiac function in the patients with HF.
出处
《现代医药卫生》
2013年第6期832-833,共2页
Journal of Modern Medicine & Health
关键词
心力衰竭
利钠肽
脑
血液
心脏功能试验
心排血量
左室射血分数
Heart failure
Natriuretic peptide
brain/blood
Heart function tests
Cardiac output
Left ventricular ejection fraction
