摘要
目的：初步评价最新的诊断技术９９Ｔｃｍ－ＥＣＤ脑 ＳＰＥＣＴ双嘧达莫负荷显像在颈内动脉系统短暂脑缺血发作（ＴＩＡ）患者中的应用价值，并与脑 ＳＰＥＣＴ静息显像和头颅 ＭＲＩ相比较。方法：对 １４例颈内动脉系统 ＴＩＡ患者在发作间期进行９９Ｔｃｍ－ＥＣＤ脑ＳＰＥＣＴ静息和双嘧达莫负荷显像及头颅ＭＲＩ检查。结果：脑ＳＰＥＣＴ双嘧达莫负荷显像与静息显像相比较，共有１０例患者在负荷状态下，局部放射性稀疏的程度较静息显像明显加重。在６例脑ＳＰＥＣＴ静息显像无异常的患者中，４例在双嘧达莫负荷情况下诱导出了与ＴＩＡ发作期临床表现相应的脑功能部位的脑血流灌注不足。与头颅ＭＲＩ比较，９例ＭＲＩ阴性的患者在脑ＳＰＥＣＴ双嘧达莫负荷显像中显示出了局部放射性稀疏。结论：本研究结果说明双嘧达莫负荷脑ＳＰＥＣＴ显像对ＴＩＡ患者脑血流储备能力的评价是有价值的。如果能应用定量或半定量的方法计算ｒＣＢＦ的变化程度，则更有临床意义。
Objective: To evaluate the value of the new technique brain SPECT with dipyridamole stress in TIA patients. Methods: 99Tcm - ECD Brain SPECT with and without dipyridamole stress, Brain MRI were performed in 14 carotid artery TIA patients. Results: Compared with baseline brain SPECT, there were altogether 10 patients who showed worsening of hypoperfusion in the dipyridamole SPECT. Among six patients with normal results in baseline SPECT, four of them were induced to show hypoperfusion areas which correlated with the TIA symptoms in dipyridamole SPECT. And dipyridamole stress SPECT was much more sensitive in comparison with Brain MRI. Focal hypoperfusion regions were found in 9 patients with negative MRI findings. Conclusion: The study suggests that dipyridamole stress SPECT is very useful in assessing cerebral blood flow reserve. It demonstrates the region of poor vascular reserve in patients with TIA. If quantitative or semi - quantitative methods were applied to calculate rCBF, it would have more clinical value.
出处
《中国临床医学》
2000年第3期280-282,共3页
Chinese Journal of Clinical Medicine
