摘要
目的 探讨穿刺活检诊断前列腺癌的形态学标准。方法 对 2 5 0例前列腺穿刺活检包括 10 0例前列腺癌进行回顾性分析 ,评价结构异常 ,细胞学改变 ,浸润和其他有诊断意义的病变四个方面共 2 0项形态学指标对诊断前列腺癌的意义。结果 2 0项形态学指标对诊断前列腺癌均有不同程度价值 ,尤以结构异常 ,核仁明显增大 ,间质及神经周围浸润最有意义。结论 前列腺癌的诊断需对多项指标全面观察后进行综合判断。
Objective To study the morphological diagnostic criteria of prostatic adenocarcinoma in needle biopsy. Methods 250 cases of prostatic needle biopsy including 100 cases of adenocarcinoma were observed retrospectively. The diagnostic significance of 20 parameters of morphological criteria including the architectural changes, cytologic features, invasion and some additional histologic features (intraepithelial neoplasm, intraluminal crystelloid body, intraluminal basophilic mucin secretion, collagen nodule and coagulative necrosis) were analyzed. Results All 20 parameters of morphological criteria had practical significance in pathologic diagnosis, the most significant ones being architectural changes, prominent nucleoli, perineural and stromal invasion. Conclusion The diagnosis of prostatic adenocarcinoma is based on a constellation of cytologic and architectural features.
出处
《中华病理学杂志》
CAS
CSCD
北大核心
2000年第4期272-275,共4页
Chinese Journal of Pathology
关键词
前列腺肿瘤
针吸活组织检查
形态学
Prostatic neoplasms
Biopsy, needle
Histology, comparative
