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农药中毒高磷酸血症需否机械通气探讨

Discussion on the Application of Mechanical Ventilation in Pesticides Poisoning Patients with Hypercapnia
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摘要 目的探讨有机磷农药中毒所致中间型综合征患者机械通气脱机后单纯性高碳酸血症时有无再用机械通气的必要。方法回顾性分析脱机后单纯性二氧化碳滞留病人36例 ,分机械通气组 (16例 )和停机观察组 (20例 ) ,对比两组继续住院日数和院内肺部感染率 ,以及停机观察组不同时间的心率、呼吸、血压、血气分析、肝肾功能和电解质。结果停机观察组的继续住院日数和院内肺部感染率均小于机械通气组 (P<0.01或P<0.05) ,停机观察组72小时的心率、呼吸、血气分析均优于停机后24小时 (P<0.001) ;血压、肝肾功能、电解质均无明显差异。结论对中间型综合征患者 ,停机后如果有单纯轻、中度二氧化碳滞留 ,可不必继续作机械通气。 Objective To discuss the application of the mechanical ventilation in pesticides poisoning patients with hypercapnia. Methods Retrospective studies were made on 36 pesticides poisoning cases who were divided at random into two groups: 16 cases treated with mechanical ventilation and 20 cases without mechanical ventilation as the control group. Comparison was made between the two groups in the days of hospitalization and lung infection during the hospitalization. Measurements were made on the heart rate, respiration rate, blood pressure, blood-gas analysis, blood electrolyte, hepatic and renal functions in the case of the control. Results Days of hospitalization and lung infection during hospitalization were much lower in the non-ventilation group than those in the ventilation group (P<0.01, P<0.05 respectively). The heart rate, respiration rate and blood-gas analysis 72 hours after the weaning were better in the non-ventilation group than those in the ventilation group (P< 0.001) while no differences were observed between the blood pressure, electrolyte, hepatic and renal functions. Conclusion Continuous mechanical ventilation was not required for the IMS patients with simple light and moderate hypercapnia when weaning from mechanical ventilation.
出处 《浙江临床医学》 2000年第10期665-666,共2页 Zhejiang Clinical Medical Journal
关键词 中间型综合征 机械通气 脱机 单纯性高碳酸血症 Intermediate syndrome Weaning Simple hypercapni
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