摘要
为探讨18F一氟代脱氧葡萄糖（18F-FDG）正电子发射计算机断层扫描（PET／CT）检查联合血清癌胚抗原（cEA）检测在结直肠癌术后复发转移诊断中的应用价值，本研究对69例临床怀疑复发转移的结直肠癌术后患者进行全身18F—FDGPET／CT检查及血清CEA检测，并将18F-FDGPET／CT检查及CEA检测结果与复发转移的最终诊断结果进行对比分析。结果显示，69例患者中，最终诊断结直肠癌术后复发转移47例。血清CEA诊断结直肠癌术后复发转移的敏感度为85．1％，特异度为59．1％；18F～FDGPET／CT诊断结直肠癌术后复发转移的敏感度为91．5％，特异度为90．9％；两者联合诊断结直肠癌术后复发转移的敏感度为97．9％，特异度为95．5％。结果表明，18F-FDGPET／CT诊断结直肠癌术后复发转移的敏感度和特异度均较血清CEA高，血清CEA对18F—FDGPET／CT诊断具有补充作用，两者联合对诊断结直肠癌术后复发转移有较高的临床应用价值。
The objective of this study was to probe into the applicable value of 18F-fluorodeoxyglueose （18F- FDG） positron emission tomography/computed tomography（PET/CT） inspection combined with serum carcinoembryonic antigen（CEA） detection for diagnosing recurrence and metastasis following the operation for colorectal carcinoma,the 69 patients who were clinically suspected with recurrence and metastasis re- ceived above combination examination, then obtained results were compared with the final diagnostic con- firmation, and analysed. As results, 47 of 69 cases were diagnosed in accordance with postoperative recur- rence and metastasis finally,the sensitivity of serum CEA detection was 85.1% ,specificity of one was 59. 1% meanwhile, that of 18 F-FDG PET/CT was 91.5%, 90.9%, respectively ; and that of the combination of both examinations was 97.9% ,95.5% respectively. Results show that the sensitivity and specificity of 18F- FDG PET/CT inspection are all higher than serum CEA, the latter has supplement role to the former in di- agnosis, thus the combination of both examinations has more confirmed value for clinically diagnosing post- operative recurrence and metastasis of colorectal carcinoma.
出处
《中国肛肠病杂志》
2013年第2期9-12,共4页
Chinese Journal of Coloproctology
关键词
结直肠癌
正电子发射计算机断层扫描
癌胚抗原
复发
转移
Colorectal carcinoma
Positron emission tomography/computed tomography
Carcinoembryon-ic antigen
Recurrence
Matastasis
