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选择性海马杏仁核切除术治疗顽固性颞叶癫痫 被引量:2

Selective Amygdalohippocampectomy for Intractable Temporal Epilepsy
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摘要 目的 探讨选择性海马杏仁核切除术治疗颞叶癫痫的机理、适应征及手术入路。方法 对20例经EEG和MR诊断为颞叶内侧癫痫病例实施海马杏仁核切除。结果 10例颞叶癫痫患者接受经颞底入路选择性海马杏仁核切除,另10例接受经颞极入路海马杏仁核切除;术后随访,所有患者癫痫发作控制满意,无手术并发症发生。结论选择性海马杏仁核切除可通过消除癫痫灶或阻断癫痫环路来治疗颞叶癫痫,深部电极提示有颞叶内侧放电或MR发现有海马硬化等颞叶内侧病变的病例适合于海马杏仁核切除,经颧弓颞底入路是相对安全的手术方式。 Objective The purpose of this paper was to evaluate the therapeutic mechanism, operative indications and surgical approach of selective amygdalonippocampectomy (SLE) in the treatment of intractable temporal epilepsy. Method Data from 20 patients who diagnosed as having intractable temporal epilepsy by EEG and MR and received SLE were analyzed retrospectively. Results Trans-zygomaticotemporal base approach was adopted in 10 patients and trans-temporal pole approach for another 10 patients. Follow-up results demonstrated that satisfactory outcomes were obtained in all of these cases. No untoward surgical complication was observed. Conclusions By removing off the epileptic foci or cutting off the epileptic cycle, SLE could be used to treat the patients with intractable epilepsy. It was also suitable for those whose depth EEGs were found to have epileptiform discharges or sclerotic changes in the hippocampus on MR imaging. Trans-zygomaticotemporal base approach might be relatively safe for this surgery.
出处 《中国临床神经外科杂志》 2000年第2期72-74,共3页 Chinese Journal of Clinical Neurosurgery
关键词 癫痫 颞叶 外科手术 显微外科手术 Epilepsy,temporal lobe Epilepsy/Surgery,operative Microsurgery
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参考文献5

  • 1Vajkoczy P,Krakow K,Stodieck S et al.Modified approach for the selective treatment of temporal lobe epilepsy: transsylvian-transcisternal mesial-en bloc resection[].Neurosurgery.1998
  • 2Wieser HG,Yasargil MG.Selective amygdalohippocampectomy as surgical treatment of mesiobasal limbic epilepsy[].Surgical Neurology.1982
  • 3Hori T,Tabuchi S,Kurosaki M et al.Subtemporal amygdalohippocampectomy for treating medically intractable temporal lobe epilepsy[].Neurosurgery.1993
  • 4Renowden SA,Matkovic Z,Adams CBT et al.Selective amygdalo-hippocampectomy for hippocampal sclerosis: postoperative MR appearance[].American Journal of Neuroradiology.1995
  • 5Yasargil MG,Wieser HG,Valavanis A et al.Surgery and results of selective amygdalohippocampectomy in one hunderd patients with nonlesional limbic epilepsy[].Neurosurgery Clinics of North America.1993

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