摘要
青光眼是四大致盲性眼病之一 ,其中原发性开角型青光眼 (POAG)为一常见类型。经各地流行病学调查和研究 ,公认高眼压、年龄、种族、家族史是 POAG的主要危险因素。近些年来 ,由于分子流行病学研究方法的引入 ,使得本病的研究有了很大的进展。本文综述了分子流行病学在 POAG病因学方面的研究。
Glaucoma is one of the major causes of blindness. Primary open angle glaucoma(POAG) is a common form of glaucoma which high intraocular pressure, age, ethnic origin and familial history are four mainly risk factors. Recently, great progress had been made in the etiology and pathogenic mechanism of POAG by using the molecular epidemiology methods. The aim of the review is to consider the application of molecular epidemiology in the studies of POAG's etiology and pathogenic mechanism.
出处
《疾病控制杂志》
2000年第3期256-258,共3页
Chinese Journal of Disease Control and Prevention
关键词
青光眼
分子流行病学
危险因素
发病机理
primary open angle glaucoma(POAG)
molecular epidemiology
risk factors
pathogenic mechanism