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持续腰大池引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血 被引量:11

Continuous lumbar drainage combined with nimodipine injection in the treatment of aneurysmal subarachnoid hemorrhage
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摘要 目的探讨持续腰大池引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血的临床效果。方法选取50例Hunt-Hess分级Ⅱ级以上的动脉瘤性蛛网膜下腔出血患者,按照随机数字表分为治疗组和对照组各25例,2组动脉瘤栓塞治疗后均给予脱水、神经保护、激素、尼莫地平等内科常规治疗。治疗组在常规治疗基础上给予持续腰大池引流,对照组给予常规腰椎穿刺。结果治疗组恢复良好率明显高于对照组,致残率和病死率明显低于对照组,2组比较差异有统计学意义(P<0.05)。结论持续腰大池引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血临床效果好,可明显改善动脉瘤性蛛网膜下腔患者的预后,降低致残率和病死率。 Objective To investigate the clinical effect of continuous lumbar drainage combined with nimodipine injection in the treatment of subarachnoid hemorrhage by aneurysms. Methods Totally 50 patients with aneurysmal subarachnoid hemorrhage (Hunt-Hess grade Ⅱ )were randomly divided into treatment group and control group according to the random number table, each of 25 cases. Both groups were given endovascular, neuroprotective, nimodipine injection, and other routine medical treatment after aneurysm treatment. Continuous lumbar drainage was given to treatment group, while the control group received routine lumbar puncture. Results The patients in treatment group received a good recovery rate,the mortality rate was lower than control group, the difference was significant (P〈0. 05). Conclusion Continuous lumbar drainage and nimodipine injection treatment has a good curative effect on aneurysmal subarachnoid hemorrhage, and can significantly improve the prognosis of aneurysmal subarachnoid and reduce the morbidity and mortality.
出处 《中国实用神经疾病杂志》 2013年第5期22-24,共3页 Chinese Journal of Practical Nervous Diseases
关键词 蛛网膜下腔出血 尼莫地平 动脉瘤 腰大池 引流 Subarachnoid hemorrhage Nimodipine injection Aneurysm Lumbar Drainage
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