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左心房收缩不同步性的影响因素与急性脑梗死发病的相关性

Study on correlation of left atrial dyssynchrony with acute cerebral infarction and its clinical impact factors
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摘要 目的探讨导致左心房收缩不同步性的临床因素,与急性脑梗死发病的临床相关性。方法对我院收治的72例急性脑梗死患者的临床资料及超声结果进行分析,并与临床上无急性脑梗死及相关性心脏疾病患者进行对比,采用SPSS17.0统计学软件进行统计学分析。结果 2组心率(HR)、左室射血分数(LVEF)、左室舒张末期内径(LVDd)及房间隔电-机械收缩时间(TIAS)比较差异无统计学意义(P>0.05),观察组收缩压(SBP)、舒张压(DBP)、左心房内径指数(LAI)、左心室质量指数(LVMI)、左房游离壁电-机械收缩时间(TLA)及左心房不同步性数据显著高于对照组,而E峰与A峰的比值(E/A)显著低于对照组,差异有统计学意义(P均<0.05)。SBP、LAI及左心房不同步性对急性脑梗死的发生存在一定影响(P均<0.05)。患者年龄、SBP及LVMI可显著增大左心房不同步性(F=151.33,P<0.05)。结论 SBP、LAI及左心房收缩不同步性是引起急性脑梗死的重要因素,其中年龄、SBP及LVMI可显著增加急性脑梗死患者左心房收缩的不同步性。 Objective To explore the clinical factors of left atrial contraction dyssynchrony and study the correlation with acute cerebral infarction. Methods Clinical data and ultrasound results of 72 patients (treatment group) were analyzed, and were compared with the data of patients without acute cerebral infarction and heart disease (control group). All the data were analyzed by SPSS 17.0 statistical software. Results There were no statistical significances of heart rate (HR), left ventricular ejection fraction(LVEF), left ventricular end-diastolic diameter(LVDd), and TIAS between the two groups (P〈0.05). The data of systolic blood pressure (SBP), diastolic blood pressure (DBP), left atrial diameter index (LAI), left ventricular mass index (LVMI), TLA and left atrlal contraction dyssynchrony in treatment group were all significantly higher than control group. The ratio of peak value E and A (E/A) of treatment group was significantly lower than control group (all P〈0.05). SBP, I.AI and left atrial contraction dyssynchrony all had some influence on the occurrence of acute cerebral infarction (all P〈 0.05). Age, SBP and LVMI increased left atrial dyssynchrony significantly(F=151.3, P〈0.01). Conclusion SBP, LAI and left atrial dyssynchrony are the important factors' to acute cerebral infarction. Age, SBP and LVMI can increase left atrial dyssynchrony significantly.
作者 张勇
出处 《中国实用神经疾病杂志》 2013年第5期10-12,共3页 Chinese Journal of Practical Nervous Diseases
关键词 血栓 急性脑梗死 左心房 不同步性 Thrombus Acute cerebral infarction Left atrial Dyssynchrony
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