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量子点:肿瘤诊断和治疗一体化荧光探针 被引量:4

Quantum dots:A fluorescent molecular probe of tumor diagnosis and treatment
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摘要 目的量子点光激发可发射荧光,具有长时间、多目标和灵敏性高等独特的光学性质,在肿瘤细胞标记和生物应用中得到了广泛应用。通过量子点标记定位肿瘤细胞,对寻找癌变部位具有指导作用。量子点作为能量供体,在肿瘤光动力学治疗研究得到关注。本文简要介绍量子点光学特性,综述量子点荧光探针在肿瘤诊断和肿瘤光动力学治疗方面应用研究。 Quantum dots (QDs) are capable of emitting fluorescence after optical excitation with unique optical properties, such as long time, much goals and high sensitivity. There is a wide range of applications of tumor cell markers and biological applications. Discovery of cancerous parts by marking tumor cells with quantum dots has important directive function in quantum dot guidance. Quantum dots as energy donor have received attention on tumor photodynamic therapy (PDT) studies. This paper briefly introduces the quantum dot optical properties, summarizes the research progress of the quantum dot fluorescent probe in tumor diagnosis and tumor PDT treatment.
作者 郝兰 王志刚
出处 《临床超声医学杂志》 2013年第3期179-182,共4页 Journal of Clinical Ultrasound in Medicine
基金 国家自然基金科研项目(81130025)
关键词 量子点 肿瘤 荧光探针 光动力学疗法 Quantum dots Tumor Fluorescent probe Photodynamic therapy
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参考文献25

  • 1Klarreich E. Biologists join the dots.Nature, 2001,413 (6855):450-452.
  • 2Samia AC , Chen X , Burda C. Semiconductor quantum dots forphotodynamic therapy. J Am Chem Soc,2003,125 (51 ): 15736 -15737.
  • 3Bakalova R, Ohba H , Zhelev Z,et al. Quantum dot anti-CDconjugates : are they potential photosensitizers or potentiators ofclassical photosensitizing agents in photodynamic therapy of cancer.Nano Letter, 2004, 4(9):1567-1573.
  • 4Rhyner MN, Smith AM,Gao X,et al. Quantum dots and multifunctionalnanoparticles: new contrast agents for tumor imaging. Nanomedicine,2006, 1(2):209-217.
  • 5Resch-Genger V,Grabolle M, Cavaliere-Jaricot S,et al. Quantumdots versus organic dyes as fluorescent labels. Nat Methods,2008,5(9):763-775.
  • 6Lim YT , Kim S , Nakayama A , et al. Selection of quantum dotwavelengths for biomedical assays and imaging. Mol Imaging,2003,2(1):50-64.
  • 7Jaiswal JK,Mattoussi H, Mauro JM,et al. Long -term multiple colorimaging of live cells using quantum dot bioconjugates. Nat Biotechnol,2003,21(1):47-51.
  • 8Wu X,Liu H,Liu J,et al. Immunofluorescent labeling of cancermarkerHer2 and other celluar targets with semiconductor quantum dots. NatBiotechnol,2003,21(1) :41-46.
  • 9Dahan M, L6vi S,Luccardini C, et al. Diffusion dynamics of glycinereceptors revealed by single quantum dot tracking. Science,2003,302(5644):442-445.
  • 10张渝阳,李荧荧,赵琨,赵玲,臧树良.碲化镉量子点作为探针研究核黄素与鲑鱼精DNA的相互作用[J].化学学报,2011,69(16):1951-1956. 被引量:4

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同被引文献25

  • 1陈良冬,李雁,袁宏银,庞代文.量子点在肿瘤研究中的应用[J].癌症,2006,25(5):651-656. 被引量:32
  • 2赵婕,曹林.CaWO_4纳米材料的合成[J].北京科技大学学报,2007,29(7):730-734. 被引量:3
  • 3Raynaud M,Chermann J C,Plata F,et al.Inhibiteurs Des Virus du Groupe Leucrmie-Sarcomes Murins.Silico-Tungstate.Paris:Comptes RenDus Hebdomedaire Des Seances De l’Acaddmie Des Sciences,1971.272,347.
  • 4Yamase T,Fujita H,Fukushima K.Inorganica Chimica Acta,1988,151:15.
  • 5Cao Lin,Yang Fuqiang,Cao Jiexin.International Journal of Minerals,Metallurgy and Materials,2009,16(4):468.
  • 6Cao Lin,Cao Jiexin,Wang Cong,et al.Bull.Mater.Sci.,2012,35(5):767.
  • 7Nan Chen,Yao He,Yuanyuan Su,Xiaoming Li,Qing Huang,Haifeng Wang,Xiangzhi Zhang,Renzhong Tai,Chunhai Fan.The cytotoxicity of cadmium-based quantum dots[J]. Biomaterials . 2011 (5)
  • 8Mallikaratchy Prabodhika,Tang Zhiwen,Kwame Sefah,Meng Ling,Shangguan Dihua,Tan Weihong.Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt’s lymphoma cells. Molecular & cellular proteomics : MCP . 2007
  • 9D Peer,JM Karp,S Hong,OC Farokhzad,R Margalit,R Langer.Nanocarriers as an emerging platform for cancer therapy. Nature nanotechnology . 2007
  • 10Xu H,Wei S,Zhu H H,et al.Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticles-assisted amplification. Chemical Communications . 2013

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