摘要
目的罗哌卡因或左布比卡因复合舒芬太尼用于硬膜外分娩镇痛的临床比较.方法随机将300例单胎初产妇分为罗哌卡因组和左布比卡因组,采用双盲法进行视觉模拟疼痛评分和运动神经阻滞的评定,并记录产程时间、生产方式和新生儿的APgra评分及脐动脉血气分析.结果 2组产妇分娩镇痛的效果良好,无显著差异(P>0.05).2组产妇产程、顺产率和剖宫产率的比较也无统计学意义(P<0.05).2组新生儿娩出后的APgar评分均正常,无统计学意义(P>0.05).但脐动脉血气中BE-B值罗哌卡因组低于左布比卡因组并有统计学意义(P<0.05).结论罗哌卡因和左布比卡因均能提供良好的镇痛效果.鉴于罗哌卡因的毒性更小,在经济条件许可下,使用罗哌卡因用于分娩镇痛会更好一些.
Objective To examine the effects of ropivacaine or levobupivacaine combined with sufentanil on epidural laboring analgesia. Methods 300 primiparous parturients were divided randomly into 2 groups： ropivacaine group and levobupivacaine group. The pain intensity was measured by visual analog scale and the degree of motor block was examined by Modified Bromaga Score using a prospective double-blind design. The labor duration and delivery types were recorded. The neonate was investigated by Apgar index. Umbilical cord artery blood gas analysis was also performed. Results The analgesia effects of ropivaeaine are same as levobupivaeaine. There are no differences in labor duration, delivery types and Apgar index. The BE-B of umbilical cord artery blood gas in ropivacaine group is significantly lower than that in levobupivaeaine group. Conclusion Ropivacaine and levobupivacaine could provide the same analgesia effects. Considering the lower toxic effects, ropivacaine is better than levobupivacaine in the treatment of laboring analgesia.
出处
《昆明医科大学学报》
CAS
2013年第2期123-125,共3页
Journal of Kunming Medical University
