摘要
目的研究在急性冠状动脉综合征患者血清中脑钠肽(BNP)、胆固醇(TC)和载脂蛋白水平潜在的联系。方法选取210例诊断为急性冠状动脉综合征的患者,并检测血清中脑钠肽(BNP),总胆固醇(TC),三酰甘油(TG),高密度脂蛋白(HDL-C),低密度脂蛋白(LDL-C)和脂蛋白a的含量,进行Pearson′s相关性分析。结果血清中BNP与TC呈显著负相关,相关系数为-0.366,P<0.001。结论在急性冠状动脉综合征患者血清中,BNP的浓度与TC呈显著负相关,临床对于严重心力衰竭患者的治疗上可以通过适当提高血清中胆固醇浓度来改善心功能。
Objective To further elucidate the relationship among plasma brain natriuretic peptide （BNP）,cholesterol and lipo- protein in patients with acute coronary syndrome. Methods Patients who were included in the study had measurement of serum levels of BNP,TC,TG, HI）I. C,I.DL-C,Lp（a）. Correlation was analysed by Pearson＇s correlation coefficient. Results we found significant negative correlation between serum levels of BNP and total cholesterol（r=-0. 366,P〈0. 001）. Conclusion BNP had significant negative correlation with TC in patients with ACS. The finding suggest that increasing serum levels of TC may have an effect on improving heart function with patients of severe heart failure.
出处
《国际检验医学杂志》
CAS
2013年第6期670-671,共2页
International Journal of Laboratory Medicine
关键词
急性冠状动脉综合征
利钠肽
脑
载脂蛋白类
acute coronary syndrome
natriuretic peptide,brain
apolipoproteins
