摘要
目的了解海军特勤人员非酒精性脂肪肝(NAFLD)发病现况及相关因素,为制定海军特勤人员非酒精性脂肪肝的防治措施提供依据。方法入选764例在解放军杭州疗养院海勤疗养区保健疗养的特勤人员,分别检测收缩压(SBP)、舒张压(DBP)、身高、体质量、总胆固醇(TC)、甘油三酯(TG)、谷丙转氨酶(ALT)、空腹血糖(FPG)及肝脏B超。结果 764例特勤人员中检出131例脂肪肝,其中轻度81人,中度50人,总发病率17.1%;轻度脂肪肝组、中度脂肪肝组的DBP、BMI、ALT、TC、TG、FPG水平均明显高于正常组,差异有显著性(P<0.05,P<0.01);正常组、轻度脂肪肝组、中度脂肪肝组超重或肥胖的发生率分别为24.3%、74.1%、96.0%,高胆固醇血症的发生率分别为11.2%、27.2%、32.0%,高甘油三酯血症的发生率分别为12.8%、45.7%、54.0%,2个脂肪肝组均明显高于正常对照组,差异有显著性(P<0.01)。多因素Logistic回归分析显示,年龄、BMI、ALT、TC、TG等5个指标是NAFLD的独立危险因素。结论海军特勤人员NAFLD发病率较高;年龄、超重或肥胖、血脂代谢紊乱是NAFLD发病的危险因素。
Objective To investigate the incidence and related risk factors of non-alcoholic fatty liver disease（NAFLD） among the navy flight crew and the submariners,so as to provide the basis for working out the measures of prevention and treatment of this disease for them.Methods A total of 533 navy flight crew and 232 submariners were selected from the sanatorium for the study.Physical examination,alanine aminotransferase（ALT）,total cholesterol（TC）,triglyceride（TG）,fasting plasma glucose（FPG）,and liver ultrasonography were carried out.Results The total incidence of non-alcoholic fatty liver disease was 17.1%（131/764）.Eighty-one,and fifty subjects were diagnosed as mild,and moderate non-alcoholic fatty liver disease respectively.The level of DBP,body mass index（BMI）,ALT,TC,TG and FPG was higher in mild,and moderate group than in normal control group（P0.05,or P0.01）.The incidence of overweight or obesity,hypercholesterolemia,and hypertriglyceridemia was higher in mild group（74.1%,27.2%,and 45.7% respectively）,and moderate group（96.0%,32.0%,and 54.0% respectively） than in normal control group（24.3%,11.2%,and 12.8% respectively,P0.01）.Logistic regression analysis demonstrated that age,BMI,ALT,TC,and TG were independent risk factors in non-alcoholic fatty liver disease.Conclusion The incidence of non-alcoholic fatty liver disease among the navy flight crew and submariners is quite high.Age,ALT,and metabolic disorders such as overweight or obesity,and hyperlipemia are the risk factors of NAFLD.
出处
《解放军预防医学杂志》
CAS
2013年第1期20-22,共3页
Journal of Preventive Medicine of Chinese People's Liberation Army
关键词
非酒精性脂肪肝
发病率
危险因素
海军特勤人员
non-alcoholic fatty liver disease
incidence
risk factors
navy flight crew and submariner
