摘要
目的:探讨原发性肝癌患者肝动脉栓塞化疗术(TACE)术后复发情况及影响预后的因素。方法:对128例行TACE术的原发性肝癌患者的临床资料进行回顾性分析,观察肿瘤复发与否对生存期的影响,分析影响预后的因素。结果:肿瘤未复发患者的生存期长于复发患者(P<0.05)。单因素分析结果显示,与预后有关的因素为:临床分期、肝功能分级、介入后AFP、总胆红素、肿瘤大小、病理类型、门静脉癌栓、碘油沉积、是否复发等9项指标;多因素分析结果显示,介入后AFP、总胆红素、病理类型、门静脉癌栓、碘油沉积是影响预后的独立因素(P<0.05)。结论:介入后AFP、总胆红素、病理类型、门静脉癌栓、碘油沉积是影响原发性肝癌栓塞化疗预后的独立因素。
Objective： To investigate the factors influencing the relapse and prognosis of primary hepatocellular carcinoma treated with transcatheter arterial chemoembolization （TACE）. Methods： We did a retrospective study on the clinical profiles of 128 patients who had primary hepatocellular carcinoma treated with TACE, and determined the impacts of tumor relapse on survival period and the prognostic factors. Results： Patients free of relapse were featured by a prolonged survival period than those who had （ P 〈 0.05 ）. Univariate regression model suggested that the clinical staging, level of liver function, post-operative AFP, total bilirubin, size of tumor, pathological category, portal cancerous thrombosis, accumulation of lipiolol and relapse were indicators of the prognosis （ all P 〈 0.05 ）. Whilst multivariate regression analysis indicated that post-operative AFP, total bilirubin, pathological category, portal cancerous thrombosis and accumulation of lipiolol might contribute to the prognosis （all P 〈 0. 05 ）. Conclusion： Post-operative AFP, total bilirubin, pathological category, portal cancerous thrombosis and accumulation of lipiolol are contributors to the prognosis of patients who have primary hepatocellular carcinoma treated with TACE.
出处
《广州医学院学报》
2012年第5期43-45,共3页
Academic Journal of Guangzhou Medical College
关键词
癌
肝细胞
原发性
经肝动脉栓塞化疗
预后
复发
hepatocellular carcinoma
primary
transcatheter arterial chemoembolization
prognosis
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