奥扎格雷钠治疗急性脑梗死的疗效及其对血浆同型半胱氨酸含量的影响被引量：2

Curative Effects of Sodium Ozagrel in the Treatment of Acute Cerebral Infarction and its Influence on Serum Homocysteins Concentrations

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摘要目的:观察奥扎格雷钠治疗急性脑梗死的疗效及对血浆同型半胱氨酸含量的影响。方法:60例急性脑梗死患者随机分为治疗组(36例)和对照(24例)组,治疗组应用奥扎格雷钠注射液,对照组用红花注射液。2组均治疗14d。于治疗前后分别进行神经功能缺损程度评分、血浆同型半胱氨酸含量的检测。结果:奥扎格雷钠组总有效率(95.3%)与红花组(70.5%)比较差异有统计学意义(P<0.03)。两组治疗后血浆同型半胱氨酸含量比治疗前显著下降(P均<0.05),但奥扎格雷钠组较丹参组下降更明显(P<0.05)。结论:奥扎格雷钠治疗急性脑梗死效果明显,并能明显降低急性脑梗死患者血浆同型半胱氨酸含量。 Objective To investigate the curative effects of Sodium Ozagrel in the treatment of acute cerebral infarction and its influence on serum homocysteins concentrations.Methods 90 patients with acute cerebral infarction were randomly divided into two treatment and control groups.Sodium Ozagrel and Radix Salviae Miltiorrhizae were respectively administrated to the patients in the treatment group（46）and the control group（44）for 14 days in addition to the basic therapy.The score of neurological deficit,the changes of serum homocysteins concentrations in the two groups were observed before and after treatment.Results After the therapy,there were significant differences（P0.01）in total effective rate between the Sodium Ozagrel group（91.3%）and the control group（70.5%）.Compared with those before treatment,the serum homocysteins concentrations decreased in both group（P0.05）,and the Sodium Ozagrel group was more significantly decreased than the other（P0.05）.Conclusion Sodium Ozagrel is an effective drug for the treatment of acute cerebral infarction and can decrease serum homocysteins concentrations.

作者赵菊霞

机构地区陕西省延安市延长县人民医院急诊科

出处《内蒙古中医药》 2013年第8期104-105,共2页 Inner Mongolia Journal of Traditional Chinese Medicine

关键词急性脑梗死奥扎格雷钠同型半胱氨酸 acute cerebral infarction sodium ozagrel homocysteins

分类号 R743.3 [医药卫生—神经病学与精神病学]

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