摘要
目的探讨认知行为治疗(Cognitive Behavioral Therapy,CBT)对精神分裂症后抑郁治疗的影响。方法对61名符合入组标准的精神分裂症后抑郁诊断的门诊患者进行随机分组。研究组(30例)给予利培酮合并认知行为治疗;对照组(31例)使用利培酮合并氟西汀治疗。8周后,运用汉密尔顿抑郁量表(HAMD)17项、PANSS量表及不良反应症状量表(TESS)对两组患者进行症状及不良反应的评定。分别在治疗第2、4、6、8周进行疗效评价;于第8周末评价副反应。结果两组的HAMD总分在治疗后均显著下降(P<0.05);两组的疗效以及不良反应比较无统计学差异(P>0.05)。结论认知行为治疗对精神分裂症后抑郁有治疗作用。
Objective To explore the Therapeutic effect of Cognitive Behavioral Therapy for patients with depression after Schizophrenia. Methods 61 outpatients with depression after Schizophrenia cases randomized. The research group （30 patients） was given drug of Risperidone and Cognitive Behavioral Therapy, the control group （31 patients） was given drugs of Risperidone and Fluoxetine. After 8 weeks, Hamilton Depression Scale （HAMD）, Positive And Negative Syndrome Scale （PANSS） as well as Treatment Emergent Symptom Scale （TESS） were used to evaluate symptoms and adverse reactions of the two groups. We evaluated the efficacy respectively in the 2,4,6,8 week and the adverse reactions in the end of the 8th week. Results HAMD total score of the two groups after treatment were significantly decreased （ P 〈 0. 05 ）, there were not statistically significant differences between the comparison of the efficacy and adverse effect of the both groups （ P 〉 0. 05 ）. Conclusions Cognitive Behavioral Therapy is effective for patients with depression after Schizophrenia.
出处
《齐齐哈尔医学院学报》
2013年第3期401-403,共3页
Journal of Qiqihar Medical University
关键词
精神分裂症
抑郁
认知行为治疗
Schizophrenia
Depression
Cognitive Behavioral Therapy
